D,L-fluorocitric acid tribenzyl ester

Base Information

• Chemical Name: D,L-fluorocitric acid tribenzyl ester
• CAS No.: 1337971-78-4
• Molecular Formula: C₂₇H₂₅FO₇
• Molecular Weight: 480.49
• Mol file: 1337971-78-4.mol

Synonyms:D,L-fluorocitric acid tribenzyl ester

Chemical Property of D,L-fluorocitric acid tribenzyl ester

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of D,L-fluorocitric acid tribenzyl ester

There total 2 articles about D,L-fluorocitric acid tribenzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.6%

malonic acid monobenzyl ester (40204-26-0) + D,L-dibenzyl 2-fluoro-3-oxosuccinate → D,L-fluorocitric acid tribenzyl ester (1337971-78-4)

Guidance literature:

With pyridine; at 20 ℃; for 3h; Heating;

DOI:10.1016/j.jfluchem.2011.07.006

Reference yield:

dibenzyl oxalate (7579-36-4) → D,L-fluorocitric acid tribenzyl ester (1337971-78-4)

Guidance literature:

Multi-step reaction with 2 steps

1.1: sodium hydride / toluene / 0.25 h / Cooling with ice

1.2: 20 °C / Heating

2.1: pyridine / 3 h / 20 °C / Heating

With pyridine; sodium hydride; In toluene;

DOI:10.1016/j.jfluchem.2011.07.006

Reference yield: 100.0%

D,L-fluorocitric acid tribenzyl ester (1337971-78-4) → fluorocitrate (357-89-1)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In ethanol; at 20 ℃; for 24h; under 2585.81 Torr;

DOI:10.1016/j.jfluchem.2011.07.006

upstream raw materials:

dibenzyl oxalate

malonic acid monobenzyl ester

Downstream raw materials:

fluorocitrate

Refernces