2-AMINO-4,6-DIMETHYLNICOTINIC ACID

Base Information

• Chemical Name: 2-AMINO-4,6-DIMETHYLNICOTINIC ACID
• CAS No.: 106837-89-2
• Molecular Formula: C8H10 N2 O2
• Molecular Weight: 166.18
• Hs Code.: 2933399090
• Mol file: 106837-89-2.mol

Synonyms:Nicotinicacid, 2-amino-4,6-dimethyl- (6CI); 2-Amino-4,6-dimethylnicotinic acid;2-Amino-4,6-dimethylpyridine-3-carboxylic acid

Chemical Property of 2-AMINO-4,6-DIMETHYLNICOTINIC ACID

Chemical Property:

• Vapor Pressure: 1.87E-05mmHg at 25°C
• Melting Point: 223°
• Refractive Index: 1.611
• Boiling Point: 348.6°Cat760mmHg
• PKA: 2.60±0.38(Predicted)
• Flash Point: 164.6°C
• PSA: 76.21000
• Density: 1.278g/cm³
• LogP: 1.56000

Purity/Quality:

98%min ^*data from raw suppliers

2-Amino-4,6-dimethylnicotinicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-AMINO-4,6-DIMETHYLNICOTINIC ACID

There total 3 articles about 2-AMINO-4,6-DIMETHYLNICOTINIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-Amino-4,6-dimethyl-3-pyridincarbonsaeure-ethylester (51076-39-2) → 2-amino-4,6-dimethylnicotinic acid (106837-89-2)

Guidance literature:

With hydrogenchloride;

Reference yield:

acetylacetone (123-54-6,81235-32-7) → 2-amino-4,6-dimethylnicotinic acid (106837-89-2)

Guidance literature:

Multi-step reaction with 2 steps

2: concentrated aqueous HCl

With hydrogenchloride;

Reference yield:

→ 2-amino-4,6-dimethylnicotinic acid (106837-89-2)

Guidance literature:

Saeure II, N2H4*H2O;

DOI:10.1039/P19750000693

upstream raw materials:

2-Amino-4,6-dimethyl-3-pyridincarbonsaeure-ethylester

acetylacetone

Downstream raw materials:

2-hydroxy-4,6-dimethylnicotinic acid

5,7-dimethyl-3H-pyrido[2,3-d]pyrimidin-4-one

4,6-dimethyl-2-ureido-nicotinic acid ; hydrochloride