Technology Process of 11-[5-[[2-(Azepan-1-yl)-1-butyl-5-cyano-4-methyl-6-oxopyridin-3-yl]methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]undecanoic acid
There total 26 articles about 11-[5-[[2-(Azepan-1-yl)-1-butyl-5-cyano-4-methyl-6-oxopyridin-3-yl]methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]undecanoic acid which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
In
tetrahydrofuran;
addn. of soln. of Cp2Co to soln. of BiPh2Cl (room temp., dropwise, 5 min), filtration; evapn. to dryness (vac., room temp.), recrystn. (EtOH); elem. anal., IR spectroscopy;
- Guidance literature:
-
In
tetrahydrofuran;
(N2), added dropwise, cooled at -40°C; filtered, dried in vac., soln. evaporated, diluted with heptane, cooled at -30°C, filtered, dried in vac.; elem. anal., IR;
- Guidance literature:
-
With
Na;
In
ammonia;
NH3 (liquid); To a suspn. of Ph2BiI in liquid NH3 sodium sand was added for about 30 min, temp. between -80 and -50°C, inert atm.;; ppt. was filtered, extd. with toluene at room temp., soln. was filtered, evapd., to dryness, recrystd. from hot abs. EtOH; elem. anal.;;
