Nateglinide

Base Information

• Chemical Name: Nateglinide
• CAS No.: 105816-06-6
• Molecular Formula: C19H27 N O3
• Molecular Weight: 317.42
• Hs Code.: 2924296000
• UNII: 41X3PWK4O2,XTM4DQP5S5
• DSSTox Substance ID: DTXSID9040687
• Nikkaji Number: J1.887.176I,J259.863I
• Wikipedia: Nateglinide
• Wikidata: Q2254797,Q27166439
• NCI Thesaurus Code: C61858
• RXCUI: 274332
• Pharos Ligand ID: XXMQZVBR5RUJ
• ChEMBL ID: CHEMBL783,CHEMBL2114389
• Mol file: 105816-06-6.mol

Synonyms:A 4166;A-4166;A4166;AY 4166;AY-4166;AY4166;DJN 608;Fastic;N-((4-isopropylcyclohexyl)carbonyl)phenylalanine;nate-glinide;nateglinide;nateglinide, (cis,D-Phe)-isomer;nateglinide, (D-Phe)-isomer;senaglinide;Starlix;Starsis

Chemical Property of Nateglinide

Chemical Property:

• PSA: 66.40000
• LogP: 3.65180
• XLogP3: 3.2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 6
• Exact Mass: 317.19909372
• Heavy Atom Count: 23
• Complexity: 393

Purity/Quality:

98% ^*data from raw suppliers

N-[[cis-4-(1-Methylethyl)cyclohexyl]carbonyl]-D-phenylalanine(NateglinideImpurity) ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Useful:

• Drug Classes: Antidiabetic Agents
• Canonical SMILES: CC(C)C1CCC(CC1)C(=O)NC(CC2=CC=CC=C2)C(=O)O
• Isomeric SMILES: CC(C)C1CCC(CC1)C(=O)N[C@H](CC2=CC=CC=C2)C(=O)O
• Recent ClinicalTrials: A Study to Assess Safety and Efficacy of ASP1941 in Combination With Nateglinide in Type 2 Diabetic Patients
• Recent EU Clinical Trials: Pragmatic Randomised 104 Week Multicentre Trial to Evaluate the Comparative Effectiveness of dapagliflozin and Standard of Care in Type 2 Diabetes. The DECIDE Study.
• Recent NIPH Clinical Trials: Comparison of effect on inflammation and Oxidative stress with Vildagliptin , Nateglinide versus Glimepiride
• Uses: N-[[cis-4-(1-Methylethyl)cyclohexyl]carbonyl]-D-phenylalanine, is an impurity of Nateglinide (N379375), which is an amino-acid derivative that stimulates insulin secretion, and used as an antidiabetic. Nateglinide USP Related Compound C.