N,N-di(hexyl)benzylamine

Base Information

• Chemical Name: N,N-di(hexyl)benzylamine
• CAS No.: 4393-08-2
• Molecular Formula: C₁₉H₃₃N
• Molecular Weight: 275.478
• Mol file: 4393-08-2.mol

Synonyms:N,N-di(hexyl)benzylamine

Chemical Property of N,N-di(hexyl)benzylamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N,N-di(hexyl)benzylamine

There total 11 articles about N,N-di(hexyl)benzylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

dihexylamine (143-16-8) + benzaldehyde (100-52-7) → N,N-di(hexyl)benzylamine (4393-08-2)

Guidance literature:

With bis(benzonitrile)palladium(II) dichloride; hydrogen; 2,2′‐biquinoline‐4,4′‐dicarboxylic acid dipotassium salt; at 100 ℃; for 24h; under 10343 Torr;

DOI:10.1016/j.tetlet.2006.03.153

Reference yield: 82.0%

benzyl azide (622-79-7) + hexan-1-ol (111-27-3) → N,N-di(hexyl)benzylamine (4393-08-2)

Guidance literature:

With C₂₂H₂₅ClIrN₃O⁽¹⁺⁾*Cl^(1-); potassium carbonate; at 130 ℃; for 24h; Sealed tube; Inert atmosphere;

DOI:10.1021/acs.joc.1c02625

Reference yield: 80.0%

benzylamine (100-46-9) + hexan-1-ol (111-27-3) → N,N-di(hexyl)benzylamine (4393-08-2)

Guidance literature:

With bis[dichloro(pentamethylcyclopentadienyl)iridium(III)]; In neat (no solvent); at 130 ℃; for 24h; Schlenk technique; Inert atmosphere;

DOI:10.1021/acs.joc.8b03137

upstream raw materials:

1-bromo-hexane

benzylamine

hexan-1-ol

dihexylamine

Downstream raw materials:

dihexylamine

Refernces

• 1、 Sitte, Nikolai A.,Bursch, Markus,Grimme, Stefan,Paradies, Jan. "Frustrated Lewis Pair Catalyzed Hydrogenation of Amides: Halides as Active Lewis Base in the Metal-Free Hydrogen Activation". supporting information. p. 159 - 162. Retrieved 2019/01/04.
• 2、 Liu, Saiwen,Chen, Ru,Deng, Guo-Jun. "Ruthenium-catalyzed formation of tertiary amines from nitriles and alcohols". supporting information; experimental part. p. 489 - 491. Retrieved 2011/06/25.