hydroxy-[(4-methylpyridin-2-yl)amino]-oxo-azanium

Base Information

• Chemical Name: hydroxy-[(4-methylpyridin-2-yl)amino]-oxo-azanium
• CAS No.: 33245-30-6
• Molecular Formula: C6H7N3O2
• Molecular Weight: 153.14
• Hs Code.: 2933399090
• Mol file: 33245-30-6.mol

Synonyms:(2E)-4-Methyl-N-nitropyridin-2(1H)-imine;2(1H)-pyridinimine, 4-methyl-N-nitro-, (2E)-;2-Pyridinamine, 4-methyl-N-nitro-;4-Methyl-N-nitropyridin-2-amin;4-Methyl-N-nitropyridin-2-amine;Hydroxy-[(4-methylpyridin-2-yl)amino]-oxo-azanium;Nsc522551;

Chemical Property of hydroxy-[(4-methylpyridin-2-yl)amino]-oxo-azanium

Chemical Property:

• Boiling Point: 300.2 °C at 760 mmHg
• Flash Point: 135.4 °C
• PSA: 70.74000
• Density: 1.335 g/cm³
• LogP: 1.58980

Purity/Quality:

99% ^*data from raw suppliers

4-METHYL-N-NITRO-2-PYRIDINAMINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of hydroxy-[(4-methylpyridin-2-yl)amino]-oxo-azanium

There total 3 articles about hydroxy-[(4-methylpyridin-2-yl)amino]-oxo-azanium which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

2-Amino-4-methylpyridine (695-34-1) → 4-methyl-2-nitraminopyridine (33245-30-6)

Guidance literature:

2-Amino-4-methylpyridine; With sulfuric acid; at 0 - 5 ℃; for 1h;

With nitric acid; In water; at -3 - 3 ℃; for 2.25h;

Reference yield:

picoline (108-89-4) → 4-methyl-2-nitraminopyridine (33245-30-6)

Guidance literature:

Multi-step reaction with 2 steps

1: xylene; sodium amide

2: concentrated sulfuric acid; nitric acid

With sulfuric acid; nitric acid; sodium amide; xylene;

Reference yield:

→ 4-methyl-2-nitraminopyridine (33245-30-6)

Guidance literature:

2-Amino-4-methyl-pyridin, rauch. HNO3 (0grad);

DOI:10.1039/j39690001505

upstream raw materials:

2-Amino-4-methylpyridine

picoline

Downstream raw materials:

5-bromo-2-nitramino-4-picoline

2-amino-5-nitro-4-picoline

2-amino-4-methyl-3-nitropyridine

4-methyl-1H-pyridin-2-one

Refernces

• 1、 Bhattacharya, Apurba,Purohit, Vikram C.,Deshpande, Prashant,Pullockaran, Annie,Grosso, John A.,DiMarco, John D.,Gougoutas, Jack Z.. "An alternate route to 2-amino-3-nitro-5-bromo-4-picoline: Regioselective pyridine synthesis via 2-nitramino-picoline intermediate". . p. 885 - 888. Retrieved 2012/12/30.