DL-2,3-DIPHENYL-SUCCINIC ACID ANHYDRIDE

Base Information

• Chemical Name: DL-2,3-DIPHENYL-SUCCINIC ACID ANHYDRIDE
• CAS No.: 101278-21-1
• Molecular Formula: C16H12 O3
• Molecular Weight: 252.269
• Hs Code.: 2917399090
• Mol file: 101278-21-1.mol

Synonyms:Succinicanhydride, 2,3-diphenyl- (6CI)

Chemical Property of DL-2,3-DIPHENYL-SUCCINIC ACID ANHYDRIDE

Chemical Property:

• Melting Point: 105.5-106.5 °C
• Refractive Index: 1.604
• Boiling Point: 431.3°Cat760mmHg
• Flash Point: 210.8°C
• PSA: 43.37000
• Density: 1.254g/cm³
• LogP: 2.63740

Purity/Quality:

98%min ^*data from raw suppliers

rac-trans-2,3-Diphenyl-succinicAcidAnhydride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of DL-2,3-DIPHENYL-SUCCINIC ACID ANHYDRIDE

There total 15 articles about DL-2,3-DIPHENYL-SUCCINIC ACID ANHYDRIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

(2S,3S)-(+)-2,3-Diphenylsuccinic acid (74431-38-2) → 2,3-diphenyl-succinic anhydride (5465-38-3,17325-42-7,17325-43-8,54282-54-1,101278-21-1)

Guidance literature:

With acetyl chloride; for 16h; Inert atmosphere; Reflux;

DOI:10.1039/c8cc00609a

Reference yield: 12.0%

carbon dioxide (124-38-9,18923-20-1) + diphenyl acetylene (501-65-5) → tetrahydro-2,5-dioxo-3,4-diphenylfuran-3-carboxylic acid (1314078-20-0) + dihydro-3,4-diphenylfuran-2,5-dione (101278-21-1)

Guidance literature:

carbon dioxide; diphenyl acetylene; With aluminium hydride; hydrogenchloride; copper(l) iodide; tetrabutylammomium bromide; In N,N-dimethyl-formamide; at 20 ℃; under 30003 Torr; Electrochemical reaction;

With hydrogenchloride; water; In N,N-dimethyl-formamide; for 3h;

DOI:10.1002/cjoc.201090285

Reference yield:

2,3-diphenylsuccinonitrile (5424-86-2) → dihydro-3,4-diphenylfuran-2,5-dione (101278-21-1)

Guidance literature:

Multi-step reaction with 2 steps

1: sulfuric acid; acetic acid / water / 0 - 130 °C / Inert atmosphere

2: acetic anhydride / 110 °C / Inert atmosphere

With sulfuric acid; acetic anhydride; acetic acid; In water;

DOI:10.1021/acs.orglett.8b00980

upstream raw materials:

carbon dioxide

diphenyl acetylene

(Z)-2,3-diphenylacrylonitrile

2,3-diphenylsuccinonitrile

Downstream raw materials:

3-oxo-2-phenyl-indan-1-carboxylic acid

Refernces

• 1、 Cotman, Andrej Emanuel,Modec, Barbara,Mohar, Barbara. "Stereoarrayed 2,3-Disubstituted 1-Indanols via Ruthenium(II)-Catalyzed Dynamic Kinetic Resolution-Asymmetric Transfer Hydrogenation". . p. 2921 - 2924. Retrieved 2018/05/28.
• 2、 Li, Chuanhua,Yuan, Gaoqing,Jiang, Huanfeng. "Electrocarboxylation of alkynes with carbon dioxide in the presence of metal salt catalysts". experimental part. p. 1685 - 1689. Retrieved 2011/07/07.