trans-4-Stilbenemethanol

Base Information

• Chemical Name: trans-4-Stilbenemethanol
• CAS No.: 101093-37-2
• Molecular Formula: C15H14O
• Molecular Weight: 210.276
• European Community (EC) Number: 625-156-2
• Nikkaji Number: J1.291.858E,J679.435A
• Wikidata: Q76311798
• Mol file: 101093-37-2.mol

Synonyms:trans-4-Stilbenemethanol;101093-37-2;4-Hydroxymethylstilbene;[4-[(E)-2-phenylethenyl]phenyl]methanol;Benzenemethanol, 4-(2-phenylethenyl)-;4-Styrylbenzyl alcohol;(E)-4-Stilbenemethanol;SCHEMBL96115;(E)-(4-Styrylphenyl)methanol;AKOS015967589;J-000323

Chemical Property of trans-4-Stilbenemethanol

Chemical Property:

• Appearance/Colour: powder
• Vapor Pressure: 4.43E-06mmHg at 25°C
• Melting Point: 155-160 °C(lit.)
• Refractive Index: 1.675
• Boiling Point: 368.5 °C at 760 mmHg
• Flash Point: 160.3 °C
• PSA: 20.23000
• Density: 1.127 g/cm³
• LogP: 3.34930
• XLogP3: 3.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 210.104465066
• Heavy Atom Count: 16
• Complexity: 208

Purity/Quality:

98%min ^*data from raw suppliers

trans-4-Stilbenemethanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22-36/37/38
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C=CC2=CC=C(C=C2)CO
• Isomeric SMILES: C1=CC=C(C=C1)/C=C/C2=CC=C(C=C2)CO
• Uses: trans-4-Stilbenemethanol is a stain/dye. Dyes and metabolites.

Technology Process of trans-4-Stilbenemethanol

There total 39 articles about trans-4-Stilbenemethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

(E)-4-styrylbenzyl acetate (1081852-38-1) → trans-4-stilbenemethanol (101093-37-2)

Guidance literature:

With zirconocene dichloride; diisobutylaluminium hydride; In tetrahydrofuran; at -20 ℃; regioselective reaction; Inert atmosphere;

DOI:10.1021/acs.orglett.8b03947

Reference yield: 92.0%

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) + para-Chlorobenzyl alcohol (873-76-7) → trans-4-stilbenemethanol (101093-37-2)

Guidance literature:

With tributyl-amine; LDH-Pd⁽⁰⁾; tetrabutylammomium bromide; at 130 ℃; for 30h;

DOI:10.1021/ja026975w

Reference yield: 90.0%

(E)-methyl 4-styrylbenzoate (1149-18-4) → trans-4-stilbenemethanol (101093-37-2)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran;

DOI:10.1021/jo0509049

upstream raw materials:

4-Styryl-benzylacetat

<4-Styryl-benzyl>-diaethylamin

bromobenzene

(4-vinyl-phenyl)-methanol

Downstream raw materials:

C₂₂H₁₆F₂

C₂₂H₁₆F₂

diphenyldisulfane

(E)-1,2-diphenyl-ethene

Refernces

• 1、 Oloyede, Hammed Olawale,G?rls, Helmar,Orighomisan Woods, Joseph Anthony,Plass, Winfried,Eseola, Abiodun Omokehinde. "N-donor 2-(Sulfonamido)benzamide ligands, their palladium(II) coordination species and C–C coupling catalysis efficiencies". . p. 336 - 344. Retrieved 2019.
• 2、 Choudary, Boyapati M.,Madhi, Sateesh,Chowdari, Naidu S.,Kantam, Mannepalli L.,Sreedhar, Bojja. "Layered double hydroxide supported nanopalladium catalyst for Heck-, Suzuki-, Sonogashira-, and Stille-type coupling reactions of chloroarenes". . p. 14127 - 14136. Retrieved 2002.
• 3、 Ko, Wonjae,Kim, Ju Hee,Yim, Guk Hee,Lee, Seong Chan,Kim, Sumin,Kwak, Minjoon,Choi, Hyunwoo,Kim, Jongchan,Antink, Wytse Hooch,Kim, Jiheon,Lee, Chan Woo,Bok, Jinsol,Jung, Yoon,Lee, Eunwon,Lee, Kug-Seung,Cho, Sung-Pyo,Kim, Do Heui,Kim, Young Gyu,Lee, Byoung-Hoon,Hyeon, Taeghwan,Yoo, Dongwon. "Controlling Multiple Active Sites on Pd?CeO2 for Sequential C?C Cross-coupling and Alcohol Oxidation in One Reaction System". . . Retrieved 2022/01/22.
• 4、 Oloyede, Hammed Olawale,Akong Akong, Raymond,Woods, Joseph Anthony Orighomisan,G?rls, Helmar,Plass, Winfried,Eseola, Abiodun Omokehinde. "New Bidentate N-Sulfonyl-Substituted Aromatic Amines as Chelate Ligand Backbones: Pd Catalyst Generation in C-C Coupling via in Situ and Precatalyst Modes". . p. 101 - 110. Retrieved 2020/07/28.