Technology Process of 1-(2,5-dideoxypentofuranosyl)-5-fluoropyrimidine-2,4(1H,3H)-dione
There total 4 articles about 1-(2,5-dideoxypentofuranosyl)-5-fluoropyrimidine-2,4(1H,3H)-dione which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogen; triethylamine;
palladium on activated charcoal;
In
methanol;
for 0.833333h;
under 760 Torr;
Ambient temperature;
DOI:10.1021/jm00182a008
- Guidance literature:
-
In
water; water-d2;
for 8h;
Ambient temperature;
thymidine phosphorylase from E. coli; sodium phosphate buffer, pH 7.4;
DOI:10.1021/jo00029a040
- Guidance literature:
-
With
thymidine phosphorylase from Escherichia coli;
In
phosphate buffer;
at 35 ℃;
for 3h;
pH=7.0;
Title compound not separated from byproducts;
DOI:10.1246/cl.2006.232