(5R,2E)-5-phenyl-5-(2-thienylsulfonyl)amino-2-pentenal

Base Information

• Chemical Name: (5R,2E)-5-phenyl-5-(2-thienylsulfonyl)amino-2-pentenal
• CAS No.: 1068150-47-9
• Molecular Formula: C₁₅H₁₅NO₃S₂
• Molecular Weight: 321.421
• Mol file: 1068150-47-9.mol

Synonyms:(5R,2E)-5-phenyl-5-(2-thienylsulfonyl)amino-2-pentenal

Chemical Property of (5R,2E)-5-phenyl-5-(2-thienylsulfonyl)amino-2-pentenal

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (5R,2E)-5-phenyl-5-(2-thienylsulfonyl)amino-2-pentenal

There total 2 articles about (5R,2E)-5-phenyl-5-(2-thienylsulfonyl)amino-2-pentenal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

N-phenylmethylene 2-thiophenesulfonamide (308293-22-3) + 1-(trimethylsiloxy)-1,3-butadiene (6651-43-0) → (5R,2E)-5-phenyl-5-(2-thienylsulfonyl)amino-2-pentenal (1068150-47-9)

Guidance literature:

N-phenylmethylene 2-thiophenesulfonamide; With C₆₈H₆₂Br₂Cu₂Fe₂P₂S₂; silver perchlorate; In dichloromethane; at 20 ℃; for 0.0833333h; Inert atmosphere;

1-(trimethylsiloxy)-1,3-butadiene; In dichloromethane; at 20 ℃; optical yield given as %ee; Inert atmosphere;

DOI:10.1021/ol8019082

Reference yield:

N-phenylmethylene 2-thiophenesulfonamide (308293-22-3) + 1-(trimethylsiloxy)-1,3-butadiene (6651-43-0) → (5R,2E)-5-phenyl-5-(2-thienylsulfonyl)amino-2-pentenal (1068150-47-9) + (5S,2E)-5-phenyl-5-(2-thienylsulfonyl)amino-2-pentenal

Guidance literature:

N-phenylmethylene 2-thiophenesulfonamide; With C₅₂H₅₄Br₂Cu₂Fe₂P₂S₂; silver perchlorate; In dichloromethane; at 20 ℃; for 0.0833333h; Inert atmosphere;

1-(trimethylsiloxy)-1,3-butadiene; In dichloromethane; at 20 ℃; optical yield given as %ee; Inert atmosphere;

DOI:10.1021/ol8019082

upstream raw materials:

N-phenylmethylene 2-thiophenesulfonamide

1-(trimethylsiloxy)-1,3-butadiene

Refernces