(E)-2-methyl-3-phenylacrylamide

Base Information Edit

Chemical Name:(E)-2-methyl-3-phenylacrylamide
CAS No.:131214-21-6
Molecular Formula:C₁₀H₁₁NO
Molecular Weight:161.203
Hs Code.:
Mol file:131214-21-6.mol

Synonyms:(E)-2-methyl-3-phenylacrylamide

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Chemical Property of (E)-2-methyl-3-phenylacrylamide Edit

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Technology Process of (E)-2-methyl-3-phenylacrylamide

There total 14 articles about (E)-2-methyl-3-phenylacrylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 101-39-3
2-methyl-3-phenyl-2-propenal

: 940-27-2,131214-21-6,131214-22-7
N-(3-dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride

Guidance literature:: 2-methyl-3-phenyl-2-propenal; With 9-aminofluorene; In toluene; at 20 ℃; for 0.5h;

With oxygen; triethylamine; In toluene; for 1.5h; Reflux;
DOI:10.1021/acs.orglett.6b02465

Reference yield:

: 200633-49-4
α-methylcinnamaldoxime

: 1197-33-7
2-methyl-3-phenyl-acrylonitrile

: 940-27-2,131214-21-6,131214-22-7
N-(3-dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride

Guidance literature:: With 10% CuO-ZnO on activated carbon; In toluene; at 100 ℃; for 4h; Inert atmosphere;
DOI:10.1016/j.tetlet.2011.05.129

Reference yield:

: 1895-97-2
2-methyl-3-phenylacrylic acid

: 131214-21-6
(E)-2-methyl-3-phenylacrylamide

Guidance literature:: 2-methyl-3-phenylacrylic acid; With chloroformic acid ethyl ester; triethylamine; In tetrahydrofuran; at 0 ℃; for 0.25h; Inert atmosphere;

With ammonium hydroxide; In tetrahydrofuran; water; at 20 ℃; for 1.5h;