Technology Process of C37H46ClN5O8
There total 21 articles about C37H46ClN5O8 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium carbonate;
In
1,2-dimethoxyethane; ethylene glycol;
at 20 ℃;
for 0.05h;
Inert atmosphere;
DOI:10.1021/jm301346z
- Guidance literature:
-
Multi-step reaction with 8 steps
1: dmap; triethylamine / dichloromethane / 1 h / 20 °C / Cooling with ice; Inert atmosphere
2: ammonium cerium (IV) nitrate / methanol / 17 h / 0 °C / Inert atmosphere
3: dmap; dicyclohexyl-carbodiimide / dichloromethane / 0 - 20 °C / Inert atmosphere
4: piperidine / N,N-dimethyl-formamide / 16 h / 20 °C / Inert atmosphere
5: trifluoroacetic acid / dichloromethane; water / 3 h / 0 °C / Inert atmosphere
6: pyridinium p-toluenesulfonate / dichloromethane / 2 h / 20 °C / Inert atmosphere
7: Acetyl bromide / dichloromethane / 4 h / 20 °C / Inert atmosphere
8: potassium carbonate / ethylene glycol; 1,2-dimethoxyethane / 0.05 h / 20 °C / Inert atmosphere
With
piperidine; dmap; ammonium cerium (IV) nitrate; Acetyl bromide; pyridinium p-toluenesulfonate; potassium carbonate; triethylamine; dicyclohexyl-carbodiimide; trifluoroacetic acid;
In
methanol; 1,2-dimethoxyethane; dichloromethane; water; ethylene glycol; N,N-dimethyl-formamide;
DOI:10.1021/jm301346z
- Guidance literature:
-
Multi-step reaction with 8 steps
1: dmap; triethylamine / dichloromethane / 1 h / 20 °C / Cooling with ice; Inert atmosphere
2: ammonium cerium (IV) nitrate / methanol / 17 h / 0 °C / Inert atmosphere
3: dmap; dicyclohexyl-carbodiimide / dichloromethane / 0 - 20 °C / Inert atmosphere
4: piperidine / N,N-dimethyl-formamide / 16 h / 20 °C / Inert atmosphere
5: trifluoroacetic acid / dichloromethane; water / 3 h / 0 °C / Inert atmosphere
6: pyridinium p-toluenesulfonate / dichloromethane / 2 h / 20 °C / Inert atmosphere
7: Acetyl bromide / dichloromethane / 4 h / 20 °C / Inert atmosphere
8: potassium carbonate / ethylene glycol; 1,2-dimethoxyethane / 0.05 h / 20 °C / Inert atmosphere
With
piperidine; dmap; ammonium cerium (IV) nitrate; Acetyl bromide; pyridinium p-toluenesulfonate; potassium carbonate; triethylamine; dicyclohexyl-carbodiimide; trifluoroacetic acid;
In
methanol; 1,2-dimethoxyethane; dichloromethane; water; ethylene glycol; N,N-dimethyl-formamide;
DOI:10.1021/jm301346z