N-ACETYL-S-BENZYL-DL-CYSTEINE

Base Information

• Chemical Name: N-ACETYL-S-BENZYL-DL-CYSTEINE
• CAS No.: 19538-71-7
• Molecular Formula: C12H15NO3S
• Molecular Weight: 253.322
• Hs Code.: 2930909090
• Mol file: 19538-71-7.mol

Synonyms:Alanine,N-acetyl-3-(benzylthio)-, DL- (8CI);DL-Cysteine, N-acetyl-S-(phenylmethyl)-;N-Acetyl-S-benzyl-DL-cysteine;

Chemical Property of N-ACETYL-S-BENZYL-DL-CYSTEINE

Chemical Property:

• Melting Point: 156 °C
• Boiling Point: 506.2 °C at 760 mmHg
• PKA: 3.37±0.10(Predicted)
• Flash Point: 259.9 °C
• PSA: 95.19000
• Density: 1.246 g/cm³
• LogP: 2.34940
• Storage Temp.: -20°C Freezer, Under inert atmosphere
• Solubility.: DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

98% ^*data from raw suppliers

N-Acetyl-S-benzyl-DL-cysteine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: N-Acetyl-S-benzyl-DL-cysteine is a useful reagent for the preparation of aryl benzamides as HIV protease inhibitors.

Technology Process of N-ACETYL-S-BENZYL-DL-CYSTEINE

There total 18 articles about N-ACETYL-S-BENZYL-DL-CYSTEINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(D)-2-Amino-3-(benzylthio)propanoic acid (3054-01-1,5680-65-9,16597-46-9,23032-53-3,25988-62-9) → Hippuric Acid (495-69-2,140480-84-8,21251-67-2,91787-63-2,66407-11-2) + N-acetyl-S-benzyl-D,L-cysteine (19538-71-7) + N-acetyl-S-benzyl-L-cysteine (19542-77-9)

Guidance literature:

im menschlichen Organismus und im Organismus von Ratten;

Reference yield:

2-amino-3-(benzylthio)propionic acid (5680-65-9,25988-62-9) → N-acetyl-S-benzyl-D,L-cysteine (19538-71-7) + N-acetyl-S-benzyl-L-cysteine (19542-77-9) + (D)-2-Amino-3-(benzylthio)propanoic acid (3054-01-1,5680-65-9,16597-46-9,23032-53-3,25988-62-9)

Guidance literature:

im menschlichen Organismus;

Reference yield:

ethyl N-acetyl-S-benzyl-D,L-cysteinate (118456-64-7) → N-acetyl-S-benzyl-D,L-cysteine (19538-71-7)

Guidance literature:

With sodium hydroxide;

upstream raw materials:

piperidine

N-Acetamidoacrylic acid

phenylmethanethiol

(D)-2-Amino-3-(benzylthio)propanoic acid

Downstream raw materials:

S-benzyl<2-(2)H1>-L-cysteine

α-deuteriated DL-S-benzylcysteine

C₁₉H₂₀N₂O₄SSe

2-acetylamino-3-mercapto-propionic acid methyl ester

Refernces

• 1、 Glass, Richard S.,Farooqui, Firdous,Sabahi, Mahmood,Ehler, Kenneth W.. "Formation of Thiocarbonyl Compounds in the Reaction of Ebselen Oxide with Thiols". . p. 1092 - 1097. Retrieved 2007/10/02.