Technology Process of 1-bromo-4-[3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl(dimethyl)silyl]benzene
There total 2 articles about 1-bromo-4-[3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl(dimethyl)silyl]benzene which
guide to synthetic route it.
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synthetic route:
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74612-30-9
chloro(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl)dimethylsilane
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253434-30-9
1-bromo-4-[3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl(dimethyl)silyl]benzene
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1,4-bis-[(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro-decyl)-dimethyl-silanyl]-benzene
- Guidance literature:
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1,4-bromoiodobenzene;
With
n-butyllithium;
In
hexane; pentane;
at 0 ℃;
for 1h;
chloro(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl)dimethylsilane;
In
tetrahydrofuran; Petroleum ether;
at 20 ℃;
DOI:10.1021/jo991548v
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253434-30-9
1-bromo-4-[3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl(dimethyl)silyl]benzene
- Guidance literature:
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Multi-step reaction with 2 steps
1.1: 79.2 percent / aq. H2PtCl6 / Heating
2.1: n-BuLi / hexane; pentane / 1 h / 0 °C
2.2: 87 percent / tetrahydrofuran; petroleum ether / 20 °C
With
dihydrogen hexachloroplatinate; n-butyllithium;
In
hexane; pentane;
1.1: Addition / 2.1: Metallation / 2.2: silylation;
DOI:10.1021/jo991548v
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253434-30-9
1-bromo-4-[3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl(dimethyl)silyl]benzene
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tris[4-{(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl)dimethylsilyl}phenyl]phosphine
- Guidance literature:
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1-bromo-4-[3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl(dimethyl)silyl]benzene;
With
n-butyllithium;
In
hexane;
at 20 ℃;
for 15h;
With
lithium bromide; phosphorous acid trimethyl ester;
In
pentane;
at 0 - 20 ℃;
Further stages.;
DOI:10.1021/jo991548v