3-n-pentoxyphenol

Base Information

• Chemical Name: 3-n-pentoxyphenol
• CAS No.: 18979-73-2
• Molecular Formula: C11H16 O2
• Molecular Weight: 180.247
• Hs Code.: 2909500000
• Mol file: 18979-73-2.mol

Synonyms:Phenol,m-(pentyloxy)- (7CI,8CI); m-Pentoxyphenol

Chemical Property of 3-n-pentoxyphenol

Chemical Property:

• Refractive Index: 1.4930 (estimate)
• Boiling Point: 273.08°C (rough estimate)
• PSA: 29.46000
• Density: 1.0044 (rough estimate)
• LogP: 2.96120
• Water Solubility.: 383.9mg/L(30 oC)

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-n-pentoxyphenol

There total 7 articles about 3-n-pentoxyphenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

1-Bromopentane (110-53-2) + recorcinol (108-46-3) → 3-(n-pentoxy)phenol (18979-73-2)

Guidance literature:

Reference yield:

recorcinol (108-46-3) → 3-(n-pentoxy)phenol (18979-73-2)

Guidance literature:

DOI:10.1021/ja01360a025

Reference yield:

3-((tert-butyldimethylsilyl)oxy)phenol (161006-18-4) → 3-(n-pentoxy)phenol (18979-73-2)

Guidance literature:

Multi-step reaction with 2 steps

1: triphenylphosphine; di-isopropyl azodicarboxylate / tetrahydrofuran / 12 h / 0 °C / Inert atmosphere

2: tetrabutyl ammonium fluoride / tetrahydrofuran / 20 °C / Inert atmosphere

With di-isopropyl azodicarboxylate; tetrabutyl ammonium fluoride; triphenylphosphine; In tetrahydrofuran; 1: |Mitsunobu Displacement;

DOI:10.1021/acs.jmedchem.1c01078

upstream raw materials:

1-methoxy-3-pentyloxy-benzene

recorcinol

1-Bromopentane

sodium 4-methoxyphenolate

Downstream raw materials:

3-Amino-5-pentyloxy-phenol

2-((3-butoxyphenoxy)methyl)quinoline

1-(2-Bromoethoxy)-3-n-pentoxybenzene

Refernces

• 1、 Nakamura, Hiromu,Sugiyama, Kouki,Ohta, Kazuchika,Yasutake, Mikio. "Phthalocyanine-based discotic liquid crystals switching from a molten alkyl chain type to a flying-seed-like type". . p. 7297 - 7306. Retrieved 2017/08/03.
• 2、 -. "[(3-alkoxy-phenoxy)-ethyl]-dialkylamine derivatives and their use as local anaesthetics". . . Retrieved 2008/06/13.