Sodium p-toluenesulfonamide

Base Information

• Chemical Name: Sodium p-toluenesulfonamide
• CAS No.: 18522-92-4
• Molecular Formula: C7H9 N O2 S . Na
• Molecular Weight: 193.202
• Hs Code.: 2935009090
• Mol file: 18522-92-4.mol

Synonyms:Benzenesulfonamide,4-methyl-, monosodium salt (9CI); p-Toluenesulfonamide, monosodium salt (8CI);p-Toluenesulfonamide, sodium deriv. (6CI); 4-Methylbenzenesulfonamidemonosodium salt; Sodium p-toluenesulfonamidate; Sodium p-toluenesulfonamide;Sodium p-toluenesulfonic acid amide; Sodium tosylamide; Toluene-4-sulfonamidemonosodium salt; Tosylamide sodium salt; p-Toluenesulfonamide sodium salt

Chemical Property of Sodium p-toluenesulfonamide

Chemical Property:

• PSA: 54.55000
• LogP: 2.81670

Purity/Quality:

99%, ^*data from raw suppliers

p-Toluenesulfonamide sodium salt ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Sodium p-toluenesulfonamide

There total 1 articles about Sodium p-toluenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

toluene-4-sulfonamide (70-55-3) → sodium p-toluenesulfonamide (18522-92-4)

Guidance literature:

With sodium methylate; for 2h; Heating;

Reference yield: 99.0%

2,2'-diiodoethyl ether (34270-90-1) + sodium p-toluenesulfonamide (18522-92-4) → 4-tosylmorpholine (6339-26-0)

Guidance literature:

In N,N-dimethyl-formamide; at 80 ℃; for 5h;

DOI:10.1021/jo00250a020

Reference yield: 95.5%

N,N'-Dimethylurea (96-31-1) + sodium p-toluenesulfonamide (18522-92-4) → N-Methyl-N'-toluene-p-sulfonylurea (13909-69-8) + methylamine (74-89-5)

Guidance literature:

at 160 ℃; for 3h; Product distribution; Rate constant; Equilibrium constant; Other temperature, other time, other ratio of reactants, activation energy, ΔH, ΔS;;

upstream raw materials:

toluene-4-sulfonamide

Downstream raw materials:

N,N'-carbonyl-bis(4-methylbenzenesulfonamide)

N-tosyl-7-bromoheptylamine

N-(9-bromo-nonyl)-toluene-4-sulfonamide

N-[(butylamino)carbonyl]-4-methyl-benzenesulfonamide

Refernces

• 1、 Wessel, Andrew J.,Schultz, Jason W.,Tang, Fengzhi,Duan, Hui,Mirica, Liviu M.. "Improved synthesis of symmetrically & asymmetrically: N -substituted pyridinophane derivatives". . p. 9923 - 9931. Retrieved 2017/12/12.
• 2、 -. "Bronchorelaxing agents based on indol- and isoquinoline derivatives". Page/Page column 22-23. . Retrieved 2010/11/25.