4-(1H-1,2,3-benzotriazol-1-yl)-5-nitrophthalonitrile

Base Information

• Chemical Name: 4-(1H-1,2,3-benzotriazol-1-yl)-5-nitrophthalonitrile
• CAS No.: 274924-71-9
• Molecular Formula: C₁₄H₆N₆O₂
• Molecular Weight: 290.241
• Mol file: 274924-71-9.mol

Synonyms:4-(1H-1,2,3-benzotriazol-1-yl)-5-nitrophthalonitrile

Chemical Property of 4-(1H-1,2,3-benzotriazol-1-yl)-5-nitrophthalonitrile

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(1H-1,2,3-benzotriazol-1-yl)-5-nitrophthalonitrile

There total 3 articles about 4-(1H-1,2,3-benzotriazol-1-yl)-5-nitrophthalonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

4-[(2-aminophenyl)amino]-5-nitro-phthalodinitrile (274924-60-6) → 4-(1H-1,2,3-benzotriazol-1-yl)-5-nitrophthalonitrile (274924-71-9)

Guidance literature:

With acetic acid; sodium nitrite; In water; at 70 ℃; for 3h;

DOI:10.1134/S1070363207090216

Reference yield:

1,2-diamino-benzene (95-54-5) → 4-(1H-1,2,3-benzotriazol-1-yl)-5-nitrophthalonitrile (274924-71-9)

Guidance literature:

Multi-step reaction with 2 steps

1: Et₃N / propan-2-ol / Heating

2: NaNO₂ / acetic acid; H₂O / 3 h / 70 °C

With triethylamine; sodium nitrite; In water; acetic acid; isopropyl alcohol;

DOI:10.1070/MC2002v012n02ABEH001538

Reference yield:

4-bromo-5-nitrophthalonitrile (206268-72-6) → 4-(1H-1,2,3-benzotriazol-1-yl)-5-nitrophthalonitrile (274924-71-9)

Guidance literature:

Multi-step reaction with 2 steps

1: Et₃N / propan-2-ol / Heating

2: NaNO₂ / acetic acid; H₂O / 3 h / 70 °C

With triethylamine; sodium nitrite; In water; acetic acid; isopropyl alcohol;

DOI:10.1070/MC2002v012n02ABEH001538

upstream raw materials:

4-[(2-aminophenyl)amino]-5-nitro-phthalodinitrile

1,2-diamino-benzene

4-bromo-5-nitrophthalonitrile

Downstream raw materials:

4-benzotriazol-1-yl-5-(4-chloro-3-methyl-phenoxy)-phthalonitrile

4-benzotriazol-1-yl-5-(4-bromo-phenoxy)-phthalonitrile

4-benzotriazol-1-yl-5-(4-chloro-3,5-dimethyl-phenoxy)-phthalonitrile

4-(1-benzotriazolyl)-5-(4-phenylphenoxy)phthalonitrile

Refernces

• 1、 Znoiko,Kambolova,Maizlish,Shaposhnikov,Abramov,Filimonov. "Nucleophilic substitution in 4-bromo-5-nitrophthalodinitrile: X. Synthesis of 4-(1-benzotriazolyl)-5-(1(2)-naphthyloxy)-phthalodinitriles and related phthalocyanines". . p. 1735 - 1740. Retrieved 2009.
• 2、 Znoiko,Maizlish,Shaposhnikov,Abramov,Voron'Ko. "Nucleophilic substitution in 4-bromo-5-nitrophthalodinitrile: VIII. Synthesis of 4-(benzotriazol-1-yl)-5-[4-(1-methyl-1-phenylethyl)phenoxy] phthalodinitrile and phthalocyanines on its basis". . p. 1623 - 1627. Retrieved 2008/03/13.