1,2-Diethoxy-1,1,2,2-tetramethyldisilane

Base Information

• Chemical Name: 1,2-Diethoxy-1,1,2,2-tetramethyldisilane
• CAS No.: 18419-84-6
• Molecular Formula: C8H22 O2 Si2
• Molecular Weight: 206.432
• Hs Code.: 2931900090
• European Community (EC) Number: 693-375-0
• DSSTox Substance ID: DTXSID10460878
• Nikkaji Number: J21.129J
• Wikidata: Q82285042
• Mol file: 18419-84-6.mol

Synonyms:1,2-Diethoxy-1,1,2,2-tetramethyldisilane;18419-84-6;Disilane,1,2-diethoxy-1,1,2,2-tetramethyl-;ethoxy-[ethoxy(dimethyl)silyl]-dimethylsilane;Disilane, 1,2-diethoxy-1,1,2,2-tetramethyl-;SCHEMBL647513;1,2-Diethoxytetramethyldisilane;DTXSID10460878;GWIVSKPSMYHUAK-UHFFFAOYSA-N;MFCD08276886;AKOS028109903;BS-42206;1,1,2,2-tetramethyl-1,2-diethoxydisilane;1, 2-diethoxy-1,1,2,2-tetramethyldisilane;1,2-Diethoxy-1,1,2,2-tetramethyldisilane, 97%;J-011803

Chemical Property of 1,2-Diethoxy-1,1,2,2-tetramethyldisilane

Chemical Property:

• Refractive Index: n20/D 1.423
• Boiling Point: 84℃/50mmHg
• Flash Point: 42°C
• PSA: 18.46000
• Density: 0.836g/mLat 25℃
• LogP: 2.54800
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 5
• Exact Mass: 206.11583301
• Heavy Atom Count: 12
• Complexity: 119

Purity/Quality:

99%min ^*data from raw suppliers

1,2-Diethoxy-1,1,2,2-tetramethyldisilane ^*data from reagent suppliers

Safty Information:

• Statements: 10

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCO[Si](C)(C)[Si](C)(C)OCC
• Uses: Disilane reagent used to prepare dimethylsilanol cross-coupling partners.1 Disilane reagent used to prepare dimethylsilanol cross-coupling partners.

Technology Process of 1,2-Diethoxy-1,1,2,2-tetramethyldisilane

There total 5 articles about 1,2-Diethoxy-1,1,2,2-tetramethyldisilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

ethanol (64-17-5) + 1,2-dichlorotetramethylsilane (4342-61-4) → 1,2-diethoxy-1,1,2,2-tetramethyldisilane (18419-84-6)

Guidance literature:

With triethylamine; In dichloromethane; at 0 ℃; for 1h;

DOI:10.1021/ol035288m

Reference yield:

ethanol (64-17-5) + 1,2-bis(chloromethyl)-1,1,2,2-tetramethylsilane (18139-99-6) → 1,2-diethoxy-1,1,2,2-tetramethyldisilane (18419-84-6)

Guidance literature:

With potassium cyanide; Heating;

DOI:10.1016/S0022-328X(00)80032-7

Reference yield:

1,1,2-Trimethyl-1,2,2-triethoxydisilan (17861-33-5) + methylmagnesium bromide (75-16-1) → 1,2-diethoxy-1,1,2,2-tetramethyldisilane (18419-84-6)

Guidance literature:

DOI:10.1021/jo01117a013

upstream raw materials:

1,1,2-Trimethyl-1,2,2-triethoxydisilan

methylmagnesium bromide

1,1,2,2-tetraethoxydimethyldisilane

ethanol

Downstream raw materials:

1,2-dichlorotetramethylsilane

1,3-diethoxy-1,1,3,3-tetramethyldisiloxane

benzoic acid ethyl ester

diethyl biphenyl-4,4'-dicarboxylate

Refernces

• 1、 Denmark, Scott E.,Kallemeyn, Jeffrey M.. "Palladium-Catalyzed Silylation of Aryl Bromides Leading to Functionalized Aryldimethylsilanols". . p. 3483 - 3486. Retrieved 2007/10/03.