Triethoxy-p-tolylsilane

Base Information

• Chemical Name: Triethoxy-p-tolylsilane
• CAS No.: 18412-57-2
• Molecular Formula: C13H22 O3 Si
• Molecular Weight: 254.401
• Hs Code.: 2931900090
• European Community (EC) Number: 833-848-2
• DSSTox Substance ID: DTXSID70405407
• Nikkaji Number: J918.723E
• Wikidata: Q82209942
• Mol file: 18412-57-2.mol

Synonyms:18412-57-2;Triethoxy-p-tolylsilane;Triethoxy(p-tolyl)silane;TRIETHOXY-P-TOLYLSILANE 97;Triethoxy-(4-methylphenyl)silane;p-tolyltriethoxysilane;4-methylphenyltriethoxysilane;TRIETHOXY(4-METHYLPHENYL)SILANE;(4-tolyl)triethoxysilane;SCHEMBL109758;Triethoxy-p-tolylsilane, 97%;DTXSID70405407;MFCD04974099;AKOS015913056;BS-44155;T3750;D92739

Chemical Property of Triethoxy-p-tolylsilane

Chemical Property:

• Vapor Pressure: 0.0155mmHg at 25°C
• Refractive Index: n20/D 1.464(lit.)
• Boiling Point: 104-106 °C1.8 mm Hg(lit.)
• Flash Point: >230 °F
• PSA: 27.69000
• Density: 0.986 g/mL at 25 °C(lit.)
• LogP: 2.25040
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 7
• Exact Mass: 254.13382109
• Heavy Atom Count: 17
• Complexity: 186

Purity/Quality:

98% ^*data from raw suppliers

Triethoxy(p-tolyl)silane >95.0%(GC) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCO[Si](C1=CC=C(C=C1)C)(OCC)OCC
• Uses: A silicon-based nucleophile shown to be reactive in Pd-catalyzed cross-coupling reactions.

Technology Process of Triethoxy-p-tolylsilane

There total 11 articles about Triethoxy-p-tolylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

ethanol (64-17-5) + (4-methylphenyl)silane (931-70-4) → p-tolyltriethoxysilane (18412-57-2)

Guidance literature:

With graphene immobilized iridium complex containing N-heterocyclic carbene ligand functionalized with pyrene; at 30 ℃; for 0.583333h;

DOI:10.1021/acscatal.7b04479

Reference yield: 89.0%

Triethoxysilane (998-30-1) + 4-tolyl iodide (624-31-7) → p-tolyltriethoxysilane (18412-57-2)

Guidance literature:

With chloro(1,5-cyclooctadiene)rhodium(I) dimer; sodium tosylate; triethylamine; In N,N-dimethyl-formamide; for 8h; Reflux;

DOI:10.1055/s-0029-1219090

Reference yield: 89.0%

Triethoxysilane (998-30-1) + 4-methylbenzenediazonium 4-methylbenzenesulfonate → p-tolyltriethoxysilane (18412-57-2)

Guidance literature:

4-methylbenzenediazonium 4-methylbenzenesulfonate; With chloro(1,5-cyclooctadiene)rhodium(I) dimer; tetra-(n-butyl)ammonium iodide; triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 2h; Inert atmosphere;

Triethoxysilane; In N,N-dimethyl-formamide; at 20 - 100 ℃; Inert atmosphere;

DOI:10.1055/s-0029-1219090

upstream raw materials:

tetraethoxy orthosilicate

para-bromotoluene

para-methylphenylmagnesium bromide

Triethoxysilane

Downstream raw materials:

(4-methylphenyl)triethylsilane

4-(3-pyridyl)toluene

4'-methyl-1,2,3,4-tetrahydro-1,1'-biphenyl

4-(4-tolyl)anisole

Refernces

• 1、 Chen, Hongyu,He, Qian,He, Xiaohui,Ji, Hongbing,Wang, Pengbo. "An ultrahigh-loading single-site Zn catalyst for efficient and ambient hydrogen generation from silanes". supporting information. p. 3828 - 3832. Retrieved 2022/03/31.
• 2、 Cho, Hyungdo,Cho, Seung Hwan,Jang, Minjae,Jeong, Jongheon,Kim, Hyunseok,Lee, Eunsung,Lim, Soobin. "Cobalt-Catalyzed Defluorosilylation of Aryl Fluorides via Grignard Reagent Formation". supporting information. p. 7387 - 7392. Retrieved 2020/10/12.