TERT-BUTYLDIMETHYLSILANOL

Base Information

• Chemical Name: TERT-BUTYLDIMETHYLSILANOL
• CAS No.: 18173-64-3
• Molecular Formula: C6H16OSi
• Molecular Weight: 132.278
• Hs Code.: 2931900090
• Mol file: 18173-64-3.mol

Synonyms:Silanol,(1,1-dimethylethyl)dimethyl- (9CI);Silanol, tert-butyldimethyl- (8CI);Dimethyl-tert-butylsilanol;tert-Butyl(hydroxy)dimethylsilane;tert-Butyldimethylsilanol;tert-Butyldimethylsilyl hydroxide;

Chemical Property of TERT-BUTYLDIMETHYLSILANOL

Chemical Property:

• Appearance/Colour: colorless transparent liquid
• Vapor Pressure: 0.0165mmHg at 25°C
• Melting Point: 18 °C
• Refractive Index: n20/D 1.424(lit.)
• Boiling Point: 142.3 °C at 760 mmHg
• PKA: 15.37±0.53(Predicted)
• Flash Point: 45 °C
• PSA: 20.23000
• Density: 0.822 g/cm³
• LogP: 1.98390

Purity/Quality:

98% ^*data from raw suppliers

tert-Butyldimethylsilanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 10-36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Uses: tert-Butyldimethylsilanol can be used as a silylating agent for the protection of hydroxyl groups via silylation. It is used:For the preparation of α-chiral ether derivatives by catalytic asymmetric allylic substitution.As an initiator for the polymerization of 1,2 benzenedicarboxaldehyde.In the synthesis of enol silyl ethers.

Technology Process of TERT-BUTYLDIMETHYLSILANOL

There total 37 articles about TERT-BUTYLDIMETHYLSILANOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1-[3-(tert-Butyl-dimethyl-silanyloxy)-propyl]-3-fluoro-pyrrolidine (920003-04-9) → 3-(3-fluoropyrrolidin-1-yl)propan-1-ol (920003-05-0) + tert-butyldimethylsilanol (18173-64-3)

Guidance literature:

With water; acetic acid; In tetrahydrofuran; at 55 ℃;

Reference yield: 99.0%

tert-butyldimethylsilane (29681-57-0) → tert-butyldimethylsilanol (18173-64-3)

Guidance literature:

With oxygen; In water; acetone; at 30 ℃; for 0.0833333h; under 760.051 Torr;

DOI:10.1246/cl.150379

Reference yield: 59.0%

tert-butyldimethylsilane (29681-57-0) → tert-butyldimethylsilanol (18173-64-3) + tert-butyldimethylsilyl chloride (18162-48-6)

Guidance literature:

With chlorine dioxyde; In acetonitrile; at 25 ℃; for 12h; Time; Inert atmosphere;

DOI:10.1134/S1070363221120069

upstream raw materials:

tert-butyldimethylsilyl chloride

C₁₅H₃₉NOSi₃

Hexamethylcyclotrisiloxane

tert.-butyl lithium

Downstream raw materials:

O-(tert-butyldimethylsilyl)-N-(2-chloroethyl)carbamate

tert-butyldimethylsilyl chloride

[Pd(N,N,N',N'-tetramethylethylenediamine)(C₆F₅)(OSiMe₂Bu(t))]

[Pd(2,2'-bipyridine)(C₆F₅)(OSiMe₂Bu(t))]

Refernces

• 1、 Good, Steffen N.,Sharpe, Robert J.,Johnson, Jeffrey S.. "Highly Functionalized Tricyclic Oxazinanones via Pairwise Oxidative Dearomatization and N-Hydroxycarbamate Dehydrogenation: Molecular Diversity Inspired by Tetrodotoxin". . p. 12422 - 12425. Retrieved 2017.
• 2、 Ciliberto, E.,Doris, K. A.,Pietro, W. J.,Reisner, G. M.,Ellis, D. E.,et al.. "?-? Interactions and Bandwidths in "Molecular Metals". A Chemical, Structural, Photoelectron Spectroscopic, and Hartree-Fock-Slater Study of Monomeric and Cofacially Joined Dimeric Silicon Phthalocyanines". . p. 7748 - 7761. Retrieved 1984.
• 3、 Zeng, Rong,Feller, Moran,Ben-David, Yehoshoa,Milstein, David. "Hydrogenation and Hydrosilylation of Nitrous Oxide Homogeneously Catalyzed by a Metal Complex". . p. 5720 - 5723. Retrieved 2017.
• 4、 Adam, Waldemar,Garcia, Hermenegildo,Mitchell, Catherine M.,Saha-Moeller, Chantu R.,Weichold, Oliver. "The selective catalytic oxidation of silanes to silanols with H2O2 activated by the Ti-beta zeolite". . p. 2609 - 2610. Retrieved 1998.
• 5、 Grabovskiy, S. A.,Kabal’nova, N. N.. "Oxidation of Triorganosilanes and Related Compounds by Chlorine Dioxide". . p. 2391 - 2402. Retrieved 2022/01/22.
• 6、 Wang, Kaikai,Zhou, Jimei,Jiang, Yuting,Zhang, Miaomiao,Wang, Chao,Xue, Dong,Tang, Weijun,Sun, Huamin,Xiao, Jianliang,Li, Chaoqun. "Selective Manganese-Catalyzed Oxidation of Hydrosilanes to Silanols under Neutral Reaction Conditions". supporting information. p. 6380 - 6384. Retrieved 2019/05/06.