Technology Process of 3-(3-cyano-4-hydroxy-5-trifluoromethoxybenzoyl)-1,1-dioxo-2,3-dihydro-1,3-benzothiazole
There total 14 articles about 3-(3-cyano-4-hydroxy-5-trifluoromethoxybenzoyl)-1,1-dioxo-2,3-dihydro-1,3-benzothiazole which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
3-(3-cyano-4-methoxy-5-trifluoromethoxybenzoyl)-1,1-dioxo-2,3-dihydro-1,3-benzothiazole;
With
lithium chloride;
In
N,N-dimethyl-formamide;
at 100 ℃;
for 1h;
With
hydrogenchloride;
In
water; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: formic acid; hydroxylamine hydrochloride / 16 h / Reflux
2: thionyl chloride / N,N-dimethyl-formamide / toluene / 6 h / 60 °C
3: triethylamine / chloroform / 17 h / 20 °C
4: 3-chloro-benzenecarboperoxoic acid / chloroform / 6 h / 20 °C
5: lithium chloride / N,N-dimethyl-formamide / 1 h / 100 °C
With
formic acid; thionyl chloride; hydroxylamine hydrochloride; triethylamine; 3-chloro-benzenecarboperoxoic acid; lithium chloride;
N,N-dimethyl-formamide;
In
chloroform; N,N-dimethyl-formamide; toluene;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: thionyl chloride / N,N-dimethyl-formamide / toluene / 6 h / 60 °C
2: triethylamine / chloroform / 17 h / 20 °C
3: 3-chloro-benzenecarboperoxoic acid / chloroform / 6 h / 20 °C
4: lithium chloride / N,N-dimethyl-formamide / 1 h / 100 °C
With
thionyl chloride; triethylamine; 3-chloro-benzenecarboperoxoic acid; lithium chloride;
N,N-dimethyl-formamide;
In
chloroform; N,N-dimethyl-formamide; toluene;
