Technology Process of (S)-methyl 11-((2-amino)-2-phenylacetamido)undecanoate hydrochloride
There total 3 articles about (S)-methyl 11-((2-amino)-2-phenylacetamido)undecanoate hydrochloride which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogenchloride;
In
methanol; water;
at 20 ℃;
for 18h;
Inert atmosphere;
DOI:10.1039/c4ob00207e
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: N-ethyl-N,N-diisopropylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / dichloromethane / 0.25 h / 0 °C / Inert atmosphere
1.2: 18 h / 20 °C / Inert atmosphere
2.1: hydrogenchloride / methanol; water / 18 h / 20 °C / Inert atmosphere
With
hydrogenchloride; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine;
In
methanol; dichloromethane; water;
DOI:10.1039/c4ob00207e
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: thionyl chloride / 4 h / 20 - 80 °C
2.1: N-ethyl-N,N-diisopropylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / dichloromethane / 0.25 h / 0 °C / Inert atmosphere
2.2: 18 h / 20 °C / Inert atmosphere
3.1: hydrogenchloride / methanol; water / 18 h / 20 °C / Inert atmosphere
With
hydrogenchloride; thionyl chloride; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine;
In
methanol; dichloromethane; water;
DOI:10.1039/c4ob00207e
