2-NAPHTHALENECARBOXYLIC ACID SODIUM SALT

Base Information

• Chemical Name: 2-NAPHTHALENECARBOXYLIC ACID SODIUM SALT
• CAS No.: 17273-79-9
• Molecular Formula: C11H8 O2 . Na
• Molecular Weight: 194.165
• Mol file: 17273-79-9.mol

Synonyms:2-Naphthalenecarboxylicacid, sodium salt (9CI); 2-Naphthoic acid, sodium salt (8CI); Sodium2-naphthalenecarboxylate; Sodium 2-naphthoate; Sodium b-naphthalenecarboxylate

Chemical Property of 2-NAPHTHALENECARBOXYLIC ACID SODIUM SALT

Chemical Property:

• Vapor Pressure: 0Pa at 25℃
• PSA: 40.13000
• Density: 1510 at 21℃
• LogP: 1.20330

Purity/Quality:

99.9% ^*data from raw suppliers

2-Naphthalenecarboxylicacidsodiumsalt ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Sodium 2-Naphthoate is the salt form of 2-Naphthalenecarboxylic Acid(N345640); has been studied for its structure-activity relationship for allosteric NMDA receptor inhibitors for potential development of NMDA receptor modulator agents for a variety of neuropsychiatric and neurological conditions.

Technology Process of 2-NAPHTHALENECARBOXYLIC ACID SODIUM SALT

There total 5 articles about 2-NAPHTHALENECARBOXYLIC ACID SODIUM SALT which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

naphthalene-2-carboxylate (93-09-4) → sodium 2-naphthalene carboxylate (17273-79-9)

Guidance literature:

With sodium cyanide; In ethanol; N,N-dimethyl-formamide; at 50 ℃; for 48h; Molecular sieve;

DOI:10.1002/bkcs.10398

Reference yield:

3Na(1+)*C27H13O11S3(3-) → 8-hydroxy-1,3,6-pyrenetrisulfonic acid trisodium salt (6358-69-6) + sodium 2-naphthalene carboxylate (17273-79-9)

Guidance literature:

With water; sodium hydroxide;

DOI:10.1021/jacs.7b07747

Reference yield:

α-naphthoic acid, sodium salt (17273-44-8) → 2,6-naphthalene dicarboxylate disodium salt (16303-32-5,52679-48-8,55831-66-8) + sodium 2-naphthalene carboxylate (17273-79-9) + naphthalene-2,3-dicarboxylic acid (17273-36-8) + naphthalene-2,3,6-tricarboxylic acid + C14H4O8(4-)*4Na(1+)

Guidance literature:

With cadmium(II) oxide; sodium iodide; at 480 ℃; for 1h; Product distribution; effect of changing the amount of sodium iodide;

DOI:10.1246/cl.1988.1933

upstream raw materials:

α-naphthoic acid, sodium salt

β-naphthaldehyde

naphthalene-2-carboxylate

sodium hydroxide

Downstream raw materials:

2,6-naphthalene dicarboxylate disodium salt

naphthalene-2,3-dicarboxylic acid

C₆H₅COC₁₀H₇

4-(2-(naphthalen-2-ylformyloxyl)ethoxy)-3-phenylfuran-2(5H)-one

Refernces

• 1、 Chang, Xihao,Guo, Chang,Peng, Lingzi,Xu, Xianghong. "Ni/Chiral Sodium Carboxylate Dual Catalyzed Asymmetric O-Propargylation". supporting information. p. 21048 - 21055. Retrieved 2021/12/14.
• 2、 Kim, Yoo-Jin,Cheon, Cheol-Hong. "Metal-free aerobic oxidative esterification of aldehydes in the presence of cyanide". . p. 2055 - 2061. Retrieved 2015/08/18.