1,3-BIS(PHENYLTHIO)PROPANE

Base Information

• Chemical Name: 1,3-BIS(PHENYLTHIO)PROPANE
• CAS No.: 28118-53-8
• Molecular Formula: C15H16S2
• Molecular Weight: 260.424
• Hs Code.: 29309099
• Mol file: 28118-53-8.mol

Synonyms:Propane,1,3-bis(phenylthio)- (6CI,7CI,8CI);1,3-Bis(phenylsulfanyl)propane;1,3-Bis(phenylthio)propane;1,1'-(propane-1,3-diyldisulfanediyl)dibenzene;1,1'-(Propane-1,3-diyldisulfanediyl)dibenzene;benzene, 1,1'-[1,3-propanediylbis(thio)]bis-;

Chemical Property of 1,3-BIS(PHENYLTHIO)PROPANE

Chemical Property:

• Appearance/Colour: clear slightly yellow liquid
• Vapor Pressure: 3.17E-07mmHg at 25°C
• Refractive Index: n20/D 1.6281(lit.)
• Boiling Point: 430.8 °C at 760 mmHg
• Flash Point: 194.6 °C
• PSA: 50.60000
• Density: 1.14 g/cm³
• LogP: 4.96110

Purity/Quality:

98%min ^*data from raw suppliers

1,3-BIS(PHENYLTHIO)PROPANE 95.00% ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,3-BIS(PHENYLTHIO)PROPANE

There total 11 articles about 1,3-BIS(PHENYLTHIO)PROPANE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

3-chloropropyl phenyl sulfide (4911-65-3) → 1,3-bis(phenylthio)propane (28118-53-8)

Guidance literature:

With aluminum oxide; at 120 ℃; for 24h;

Reference yield: 86.0%

thiophenol (108-98-5) + allyl bromide (106-95-6) → 1,3-bis(phenylthio)propane (28118-53-8)

Guidance literature:

With silica nanoparticle (1 wtpercent); at 20 ℃; for 1h; regioselective reaction;

DOI:10.1016/j.tetlet.2008.10.110

Reference yield: 85.0%

allyl iodid (556-56-9) + thiophenol (108-98-5) → 1,3-bis(phenylthio)propane (28118-53-8) + diphenyldisulfane (882-33-7)

Guidance literature:

With water; silica gel; for 20h; regioselective reaction; Mechanism;

DOI:10.3762/bjoc.10.5

upstream raw materials:

thiophenol

1,3-dibromo-propane

sodium thiophenolate

3-chloropropyl phenyl sulfide

Downstream raw materials:

2-<1-(phenylthio)cyclopropyl>-2-hexanol

cyclopropylphenylsulfide

1,3-bis-benzenesulfonyl-propane

1-Deuterocyclopropylphenylsulfid

Refernces

• 1、 Gholinejad, Mohammad. "One-Pot Copper-Catalysed Thioetherification of Aryl Halides Using Alcohols and Lawesson's Reagent in Diglyme". . p. 4162 - 4167. Retrieved 2015/06/30.
• 2、 Banerjee, Subhash,Das, Jayanta,Alvarez, Richard P.,Santra, Swadeshmukul. "Silica nanoparticles as a reusable catalyst: A straightforward route for the synthesis of thioethers, thioesters, vinyl thioethers and thio-Michael adducts under neutral reaction conditions". experimental part. p. 302 - 306. Retrieved 2010/06/13.