Methyl-1,2-cyclopentene oxide

Base Information

• Chemical Name: Methyl-1,2-cyclopentene oxide
• CAS No.: 16240-42-9
• Molecular Formula: C6H10 O
• Molecular Weight: 98.1448
• Hs Code.: 2932999099
• European Community (EC) Number: 626-102-0
• DSSTox Substance ID: DTXSID30401228
• Nikkaji Number: J714.597G
• Mol file: 16240-42-9.mol

Synonyms:16240-42-9;1-methyl-6-oxabicyclo[3.1.0]hexane;Methyl-1,2-cyclopentene oxide;1-Methyl-6-oxa-bicyclo[3.1.0]hexane;MFCD02683484;METHYL-1 2-CYCLOPENTENE OXIDE 99;6-Oxabicyclo[3.1.0]hexane, 1-methyl-;methylcyclopentene oxide;1-methyl-cyclopentene oxide;DTXSID30401228;TQP0661;AKOS015913020;Methyl-1,2-cyclopentene oxide, 99%;AT16552;SB34078;SY007917;CS-0112282;EN300-209516

Chemical Property of Methyl-1,2-cyclopentene oxide

Chemical Property:

• Refractive Index: n20/D 1.431(lit.)
• Boiling Point: 113 °C(lit.)
• Flash Point: 54 °F
• PSA: 12.53000
• Density: 0.914 g/mL at 25 °C(lit.)
• LogP: 1.32780
• Storage Temp.: 2-8°C
• XLogP3: 1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 98.073164938
• Heavy Atom Count: 7
• Complexity: 100

Purity/Quality:

NLT 98% ^*data from raw suppliers

1-Methyl-6-oxa-bicyclo[3.1.0]hexane 95% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: F,Xi
• Statements: 11-36/37/38
• Safety Statements: 16-26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC12CCCC1O2

Technology Process of Methyl-1,2-cyclopentene oxide

There total 10 articles about Methyl-1,2-cyclopentene oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

1-methylcyclopent-1-ene (693-89-0) → 1,2-epoxy-1-methylcyclopentane (16240-42-9)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 5 - 20 ℃; Inert atmosphere;

Reference yield: 80.0%

(C4H9)3SnOC5H7ClCH3 → 1,2-epoxy-1-methylcyclopentane (16240-42-9)

Guidance literature:

decompn. at 170°C for 0.5 h;

DOI:10.1016/S0022-328X(00)86886-2

Reference yield: 75.0%

(C4H9)3SnOC5H7BrCH3 → 1,2-epoxy-1-methylcyclopentane (16240-42-9)

Guidance literature:

decompn. at 80°C for 0.5 h;

DOI:10.1016/S0022-328X(00)86886-2

upstream raw materials:

1-methylcyclopent-1-ene

(+/-)-2t-chloro-1-methyl-cyclopentan-r-ol

diethyl ether

Cycloheptene

Refernces

• 1、 Duan, Shengquan,Feng, Xichun,Gonzalez, Miguel,Bader, Scott,Hayward, Cheryl,Ljubicic, Tomislav,Lu, Jiangping,Mustakis, Jason,Maloney, Mark,Rainville, Joseph,Zhang, Xin. "Developing a multistep continuous manufacturing process for (1R,2R)-2-amino-1-methylcyclopentan-1-ol". . p. 2734 - 2744. Retrieved 2020.
• 2、 Macmillan, David W. C.,Oswood, Christian J.. "Selective Isomerization via Transient Thermodynamic Control: Dynamic Epimerization of trans to cis Diols". supporting information. p. 93 - 98. Retrieved 2022/01/03.
• 3、 -. "Method for epoxidizing small-molecular olefin". Paragraph 0194-0195; 0214-0215. . Retrieved 2021/06/06.