Benzamide, N,3-dihydroxy-

Base Information

• Chemical Name: Benzamide, N,3-dihydroxy-
• CAS No.: 16060-55-2
• Molecular Formula: C7H7 N O3
• Molecular Weight: 153.137
• Hs Code.: 2924299090
• Mol file: 16060-55-2.mol

Synonyms:Benzohydroxamicacid, m-hydroxy- (8CI); 3-Hydroxybenzohydroxamic acid;3-Hydroxyphenylhydroxamic acid; m-Hydroxybenzohydroxamic acid

Chemical Property of Benzamide, N,3-dihydroxy-

Chemical Property:

• PSA: 73.05000
• LogP: 1.08600

Purity/Quality:

99% ^*data from raw suppliers

N,3-dihydroxybenzamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzamide, N,3-dihydroxy-

There total 9 articles about Benzamide, N,3-dihydroxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

N-(benzyloxy)-3-hydroxybenzamide (932380-42-2) → 3-hydroxy-benzohydroxamic acid (16060-55-2)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol; at 23 ℃; for 0.5h;

DOI:10.1016/j.bmcl.2006.11.053

Reference yield:

3-(benzyloxy)-N-hydroxybenzamide → 3-hydroxy-benzohydroxamic acid (16060-55-2)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In methanol;

DOI:10.1039/c5ra25256c

Reference yield:

C17H16O5 → 3-hydroxy-benzohydroxamic acid (16060-55-2)

Guidance literature:

Multi-step reaction with 2 steps

1: hydroxylamine hydrochloride / methanol

2: palladium 10% on activated carbon; hydrogen / methanol

With palladium 10% on activated carbon; hydroxylamine hydrochloride; hydrogen; In methanol;

DOI:10.1039/c5ra25256c

upstream raw materials:

ethyl-3-hydroxybenzoate

piloty's acid

meta-hydroxybenzaldehyde

N-(benzyloxy)-3-hydroxybenzamide

Refernces

• 1、 Orlowska, Ewelina,Roller, Alexander,Wiesinger, Hubert,Pignitter, Marc,Jirsa, Franz,Krachler, Regina,Kandioller, Wolfgang,Keppler, Bernhard K.. "Benzoic hydroxamate-based iron complexes as model compounds for humic substances: Synthesis, characterization and algal growth experiments". . p. 40238 - 40249. Retrieved 2016/05/24.
• 2、 Rose, Nathan R.,Ng, Stanley S.,Mecinovi?, Jasmin,Liénard, Beno?t M. R.,Bello, Simon H.,Sun, Zhe,McDonough, Michael A.,Oppermann, Udo,Schofield, Christopher J.. "Inhibitor scaffolds for 2-oxoglutarate-dependent histone lysine demethylases". supporting information; experimental part. p. 7053 - 7056. Retrieved 2009/11/30.