C₁₂H₁₈O₄

Base Information

• Chemical Name: C₁₂H₁₈O₄
• CAS No.: 1360452-45-4
• Molecular Formula: C₁₂H₁₈O₄
• Molecular Weight: 226.273
• Mol file: 1360452-45-4.mol

Synonyms:C₁₂H₁₈O₄

Chemical Property of C₁₂H₁₈O₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of C₁₂H₁₈O₄

There total 1 articles about C₁₂H₁₈O₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(+)-proto-quercitol (488-73-3) → C12H18O4 (1360452-45-4)

Guidance literature:

Multi-step reaction with 2 steps

1: toluene-4-sulfonic acid / N,N-dimethyl-formamide / 25 h / 20 - 80 °C

2: trifluoromethylsulfonic anhydride / pyridine / 12 h / -10 °C / Inert atmosphere

With trifluoromethylsulfonic anhydride; toluene-4-sulfonic acid; In pyridine; N,N-dimethyl-formamide;

DOI:10.1016/j.bmcl.2012.01.007

Reference yield: 100.0%

C12H18O4 (1360452-45-4) → (1R,2S,3S,4S)-5-cyclohexene-1,2,3,4-tetrol (526-87-4,4782-74-5,4782-75-6,4782-76-7,4942-61-4,4942-62-5,6090-98-8,7586-48-3,25348-64-5,80338-90-5,123238-09-5,129829-51-2,133319-93-4,137567-79-4,138258-55-6,139559-64-1,140923-39-3,129829-50-1)

Guidance literature:

With hydrogenchloride; In methanol; at 20 ℃; for 4h;

DOI:10.1016/j.bmcl.2012.01.007

Reference yield:

C12H18O4 (1360452-45-4) → D-chiro-inositol

Guidance literature:

Multi-step reaction with 2 steps

1: osmium(VIII) oxide; 4-methylmorpholine N-oxide / water; tert-butyl alcohol / 12 h / 0 °C

2: Amberlyst-15 resin / methanol; water / 3 h / 20 °C

With osmium(VIII) oxide; 4-methylmorpholine N-oxide; In methanol; water; tert-butyl alcohol;

DOI:10.1016/j.bmcl.2012.01.007

upstream raw materials:

(+)-proto-quercitol

Downstream raw materials:

(1R,2S,3S,4S)-5-cyclohexene-1,2,3,4-tetrol

Refernces

• 1、 Kuno, Shinichi,Higaki, Katsumi,Takahashi, Atsushi,Nanba, Eiji,Ogawa, Seiichiro. "Potent chemical chaperone compounds for GM1-gangliosidosis: N-substituted (+)-conduramine F-4 derivatives". . p. 306 - 310. Retrieved 2015/03/18.