Tribenzyl phosphite

Base Information

• Chemical Name: Tribenzyl phosphite
• CAS No.: 15205-57-9
• Molecular Formula: C21H21 O3 P
• Molecular Weight: 352.37
• Hs Code.: 2920901900
• European Community (EC) Number: 604-823-1
• DSSTox Substance ID: DTXSID10934408
• Nikkaji Number: J70.234J
• Wikidata: Q72509854
• Mol file: 15205-57-9.mol

Synonyms:tribenzyl phosphite;15205-57-9;Tribenzylphosphite;Phosphorous acid tribenzyl ester;Phosphorous acid, tris(phenylmethyl) ester;SCHEMBL194803;DTXSID10934408;KKFOMYPMTJLQGA-UHFFFAOYSA-N;MFCD19440712;AKOS015951299;AS-10739;CS-0375651;EN300-1659369

Chemical Property of Tribenzyl phosphite

Chemical Property:

• Vapor Pressure: 2.76E-08mmHg at 25°C
• Melting Point: 52℃
• Boiling Point: 462.3ºC at 760 mmHg
• Flash Point: 290.7ºC
• PSA: 41.28000
• LogP: 5.86370
• XLogP3: 4.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 9
• Exact Mass: 352.12283153
• Heavy Atom Count: 25
• Complexity: 282

Purity/Quality:

99.9% ^*data from raw suppliers

Tribenzylphosphite 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C(C=C1)COP(OCC2=CC=CC=C2)OCC3=CC=CC=C3

Technology Process of Tribenzyl phosphite

There total 10 articles about Tribenzyl phosphite which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

benzyl alcohol (100-51-6,185532-71-2) → tribenzyl phosphite (15205-57-9)

Guidance literature:

With Hexamethylphosphorous triamide; at 100 ℃; for 2h;

Reference yield: 81.0%

diethyl ester of 2-phenylethynylphosphonous acid (51104-80-4) + benzyl alcohol (100-51-6,185532-71-2) → tribenzyl phosphite (15205-57-9) + phenylacetylene (536-74-3)

Guidance literature:

With sodium phenyl-methanolate; Product distribution; Heating; oth. alcohols;

Reference yield: 81.0%

benzyl alcohol (100-51-6,185532-71-2) → tribenzyl phosphite (15205-57-9)

Guidance literature:

With N,N-diethylaniline; In diethyl ether; at 0 ℃; for 2h;

DOI:10.1016/0040-4020(82)85087-4

upstream raw materials:

pyridine

benzyl alcohol

diethyl ester of 2-bromo-1-phenylethenylphosphonous acid

sodium phenyl-methanolate

Downstream raw materials:

Dibenzyl phosphite

Pentabenzyloxyphosphoran

(2-Chloro-acetyl)-phosphoramidic acid monobenzyl ester

4-(Bis-benzyloxy-phosphoryl)-4-oxo-butyric acid methyl ester

Refernces

• 1、 Gefflaut, Thierry,Lemaire, Marielle,Valentin, Marie-Lise,Bolte, Jean. "A novel efficient synthesis of dihydroxyacetone phosphate and bromoacetol phosphate for use in enzymatic aldol syntheses". . p. 5920 - 5922. Retrieved 1997.
• 2、 Benech,El Manouni,Leroux. "-". . p. 295 - 298. Retrieved 1996.
• 3、 Liu, Yu,Tang, Ke-Wen,Wong, Wai-Yeung,Xie, Jun,Xiong, Biquan,Xu, Shipan,Xu, Weifeng. "Silver-Catalyzed Regioselective Phosphorylation of para-Quinone Methides with P(III)-Nucleophiles". . p. 14983 - 15003. Retrieved 2021/11/12.
• 4、 Schwenger, Alexander,Frey, Wolfgang,Richert, Clemens. "Reagents with a Crystalline Coat". supporting information. p. 13706 - 13709. Retrieved 2016/10/26.