1-phenylbut-3-enyl methanesulfonate

Base Information

• Chemical Name: 1-phenylbut-3-enyl methanesulfonate
• CAS No.: 1064138-56-2
• Molecular Formula: C₁₁H₁₄O₃S
• Molecular Weight: 226.296
• Mol file: 1064138-56-2.mol

Synonyms:1-phenylbut-3-enyl methanesulfonate

Chemical Property of 1-phenylbut-3-enyl methanesulfonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-phenylbut-3-enyl methanesulfonate

There total 3 articles about 1-phenylbut-3-enyl methanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

1-Phenyl-3-buten-1-ol (80735-94-0,936-58-3) + methanesulfonyl chloride (124-63-0) → 1-phenylbut-3-enyl methanesulfonate (1064138-56-2)

Guidance literature:

With triethylamine; In dichloromethane; at 0 ℃; for 0.5h; Inert atmosphere;

Reference yield:

benzaldehyde (100-52-7) → 1-phenylbut-3-enyl methanesulfonate (1064138-56-2)

Guidance literature:

Multi-step reaction with 2 steps

1: zinc; ammonium chloride / tetrahydrofuran; water / 1 h / 20 °C

2: triethylamine / dichloromethane / 0 °C

With ammonium chloride; triethylamine; zinc; In tetrahydrofuran; dichloromethane; water;

DOI:10.1021/acs.orglett.6b03372

Reference yield:

bis(methanesulfonyl)peroxide (1001-62-3) + 4-Phenylbut-1-ene (768-56-9) → 1-phenylbut-3-enyl methanesulfonate (1064138-56-2)

Guidance literature:

With trimethylsilyl acetate; copper (I) acetate; In dichloromethane; at 23 ℃; for 12h; Inert atmosphere;

DOI:10.1021/jacs.9b09496

upstream raw materials:

1-Phenyl-3-buten-1-ol

methanesulfonyl chloride

benzaldehyde

bis(methanesulfonyl)peroxide

Downstream raw materials:

tert-butyl (+/-)-2-phenyl-2-(1-phenylbut-3-enyl)hydrazinecarboxylate

N-allyl-N-(tert-butoxycarbonyl)-1-phenylbut-3-en-1-ylamine

1-Phenyl-3-buten-1-ol

(1-azidobut-3-en-1-yl)benzene

Refernces

• 1、 Tanwar, Lalita,B?rgel, Jonas,Ritter, Tobias. "Synthesis of Benzylic Alcohols by C-H Oxidation". supporting information. p. 17983 - 17988. Retrieved 2019/11/14.
• 2、 Spangenberg, Thomas,Breit, Bernhard,Mann, Andre. "Hydroformylation of homoallylic azides: A rapid approach toward alkaloids". supporting information; experimental part. p. 261 - 264. Retrieved 2009/08/08.