Pregnanolone 3-β-D-Glucuronide

Base Information

• Chemical Name: Pregnanolone 3-β-D-Glucuronide
• CAS No.: 31329-54-1
• Molecular Formula: C₂₇H₄₂O₈
• Molecular Weight: 494.626
• Mol file: 31329-54-1.mol

Synonyms:3α-hydroxy-5β-pregnane-20-one-3-glucuronide

Chemical Property of Pregnanolone 3-β-D-Glucuronide

Chemical Property:

• Boiling Point: 663.2±55.0 °C(Predicted)
• PKA: 2.82±0.70(Predicted)
• Density: 1.30±0.1 g/cm3(Predicted)

Purity/Quality:

99% ^*data from raw suppliers

Pregnanolone3-β-D-Glucuronide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: Pregnanolone 3-β-D-Glucuronide is the glucuronide conjugate and metabolite of the Pregnanolone (P711300).

Technology Process of Pregnanolone 3-β-D-Glucuronide

There total 2 articles about Pregnanolone 3-β-D-Glucuronide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Progesterone (57-83-0) → pregnanedione (128-23-4) + 3β-hydroxy-5β-pregnan-20-one (128-21-2) + pregnanediol (80-92-2) + pregnadiol (80-89-7,80-90-0,80-92-2,516-53-0,566-56-3,566-57-4,566-58-5,4406-36-4,4479-11-2,4707-80-6,6251-84-9,25908-35-4,28818-70-4,36027-66-4,38270-91-6,38270-97-2,52746-43-7,55569-11-4,55660-10-1,73745-18-3,98048-13-6,80-91-1) + PREGNANOLONE (128-20-1,128-21-2,516-54-1,516-55-2,4243-94-1,4320-08-5,4406-35-3,4406-37-5,4469-03-8,13089-85-5,13089-86-6,14615-01-1,21788-58-9,24557-99-1,25126-79-8,26961-00-2,36027-63-1,39845-99-3,40135-22-6,72691-57-7,81076-02-0,95118-68-6,110350-90-8) + 3α-hydroxy-5β-pregnane-20-one-3-glucuronide (31329-54-1)

Guidance literature:

With phosphate buffer; (S)-2-[3]pyridyl-pyrrolidine-1-carboxylic acid amide; α-D-glucose 6-phosphate; bovine liver tissue supernatant; NADP; UDP-glucuronic acid; at 37 ℃; for 5h; Product distribution; <14C>labeled;

DOI:10.1016/0039-128X(82)90041-1

Reference yield:

→ (2S,3S,4S,5R,6R)-6-((3S,5S,10S,13S)-17-Acetyl-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-3-yloxy)-3,4,5-trihydroxy-tetrahydro-pyran-2-carboxylic acid (31300-86-4,31300-87-5,31329-54-1,39605-78-2,69460-19-1)

Guidance literature:

16, NaOCH3;

DOI:10.1016/S0008-6215(00)81557-8

upstream raw materials:

Progesterone

Refernces