N1,N1-Dipropylethane-1,2-diamine

Base Information

• Chemical Name: N1,N1-Dipropylethane-1,2-diamine
• CAS No.: 14165-22-1
• Molecular Formula: C8H20 N2
• Molecular Weight: 144.26
• Hs Code.: 2921290000
• European Community (EC) Number: 679-076-8
• DSSTox Substance ID: DTXSID30931151
• Mol file: 14165-22-1.mol

Synonyms:14165-22-1;N1,N1-Dipropylethane-1,2-diamine;2-(Di-n-propylamino)ethylamine;N',N'-dipropylethane-1,2-diamine;N,N-di(n-propyl)ethylenediamine;2-DIPROPYLAMINOETHYLAMINE;N1,N1-Dipropyl-1,2-ethanediamine;(2-aminoethyl)dipropylamine;N,N-dipropylethane-1,2-diamine;N,N-dipropylethylenediamine;2-(dipropylamino)ethylamine;SCHEMBL578516;N,N-Dipropyl-1,2-ethanediamine;DTXSID30931151;DMDXQHYISPCTGF-UHFFFAOYSA-N;MFCD00047951;1,2-Ethanediamine,N1,N1-dipropyl-;AKOS000143070;AS-81260;N~1~,N~1~-Dipropylethane-1,2-diamine;CS-0199319;E84046;EN300-863872;A885577;N(1),N(1)-Dipropyl-1,2-ethanediamine, AldrichCPR

Chemical Property of N1,N1-Dipropylethane-1,2-diamine

Chemical Property:

• Melting Point: 68-70 °C
• Refractive Index: 1.4400
• Boiling Point: 200.4°Cat760mmHg
• PKA: 10.21±0.10(Predicted)
• Flash Point: 74.3°C
• PSA: 29.26000
• Density: 0.809g/cm³
• LogP: 1.76740
• Sensitive.: Air Sensitive
• Water Solubility.: Fully miscible in water.
• XLogP3: 1.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 6
• Exact Mass: 144.162648646
• Heavy Atom Count: 10
• Complexity: 58.3

Purity/Quality:

99%, ^*data from raw suppliers

2-(Dipropylamino)ethylamine ^*data from reagent suppliers

Safty Information:

• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCN(CCC)CCN
• Uses: 2-(Di-n-propylamino)ethylamine is a useful reagent for preparing supramolecular microtubes.

Technology Process of N1,N1-Dipropylethane-1,2-diamine

There total 11 articles about N1,N1-Dipropylethane-1,2-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

(N,N-dipropylamino)acetonitrile (18071-35-7) → N,N-dipropylethanediamine (14165-22-1)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; at -78 - 20 ℃; for 4h; Inert atmosphere;

DOI:10.1016/j.ejmech.2011.07.037

Reference yield: 74.0%

N-(2-dipropylamino-ethyl)-phthalimide (97020-70-7) → N,N-dipropylethanediamine (14165-22-1)

Guidance literature:

With hydrazine; In ethanol; for 2h; Heating / reflux;

Reference yield:

2-dipropylaminoethyl bromide hydrobromide (22511-39-3) → N,N-dipropylethanediamine (14165-22-1)

Guidance literature:

With ammonia;

upstream raw materials:

ethyleneimine

N,N-dipropylamine hydrochloride

di-n-propylamine

2-dipropylaminoethyl bromide hydrobromide

Downstream raw materials:

N'-(4-Methyl-6-phenyl-pyridazin-3-yl)-N,N-dipropyl-ethane-1,2-diamine; compound with oxalic acid

methyl 4-((2-(dipropylamino)ethyl)carbamoyl)benzoate

lithium 4-((2-(dipropylamino)ethyl)carbamoyl)benzoate

N₁-((5S,8S,11S)-5,8-diisobutyl-3,13-dimethyl-4,7,10-trioxo-2-oxa-3,6,9-triazatetradecan-11-yl)-N₄-(2-(dipropylamino)ethyl)terephthalamide

Refernces

• 1、 -. "TRICYCLIC 1,2,4-TRIAZINE OXIDES AND COMPOSITIONS THEREFROM FOR THERAPEUTIC USE IN CANCER TREATMENTS". Page/Page column 169. . Retrieved 2008/06/13.
• 2、 Pasini,Coda,Colò,Ferrini,Gl?sser. "Pharmacologic action of new derivatives chemically related to guanethidine". . p. 673 - 685. Retrieved 2007/10/04.