trans-N-Methyl-5-phenyl-4-penten-1-amine

Base Information

• Chemical Name: trans-N-Methyl-5-phenyl-4-penten-1-amine
• CAS No.: 122333-64-6
• Molecular Formula: C₁₂H₁₇N
• Molecular Weight: 175.274
• Mol file: 122333-64-6.mol

Synonyms:trans-N-Methyl-5-phenyl-4-penten-1-amine

Chemical Property of trans-N-Methyl-5-phenyl-4-penten-1-amine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of trans-N-Methyl-5-phenyl-4-penten-1-amine

There total 5 articles about trans-N-Methyl-5-phenyl-4-penten-1-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

(E)-5-Phenyl-pent-4-enoic acid methylamide (131529-91-4) → trans-N-Methyl-5-phenyl-4-penten-1-amine (122333-64-6)

Guidance literature:

With lithium aluminium tetrahydride;

DOI:10.1021/ja00009a041

Reference yield:

trans-3-phenylprop-2-enyl chloride (21087-29-6) → trans-N-Methyl-5-phenyl-4-penten-1-amine (122333-64-6)

Guidance literature:

Multi-step reaction with 4 steps

1: 75 percent

2: 75 percent / NaCl / dimethylsulfoxide; H₂O / 6 h / Heating

3: 95 percent / sodium methoxide / methanol / 72 h

4: 95 percent / lithium aluminum hydride (LAH)

With lithium aluminium tetrahydride; sodium methylate; sodium chloride; In methanol; water; dimethyl sulfoxide;

DOI:10.1021/ja00009a041

Reference yield:

(E)-ethyl 5-phenylpent-4-enoate (22768-07-6,121746-04-1,93845-04-6) → trans-N-Methyl-5-phenyl-4-penten-1-amine (122333-64-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / sodium methoxide / methanol / 72 h

2: 95 percent / lithium aluminum hydride (LAH)

With lithium aluminium tetrahydride; sodium methylate; In methanol;

DOI:10.1021/ja00009a041

upstream raw materials:

(E)-5-Phenyl-pent-4-enoic acid methylamide

trans-3-phenylprop-2-enyl chloride

(E)-ethyl 5-phenylpent-4-enoate

diethyl (E)-cinnamyl malonate

Downstream raw materials:

trans-N,N-dimethyl-5-phenyl-4-penten-1-amine

N-Methyl-2-(phenylmethyl)pyrrolidine

N-methyl-2-phenylpiperidine

cis-N-Methyl-5-phenyl-4-penten-1-amine

Refernces

• 1、 Lewis, Frederick D.,Dasharatha Reddy,Schneider, Siegfried,Ga, Michael. "Photophysical and photochemical behavior of intramolecular-styrene-amine exciplexes". . p. 3498 - 3506. Retrieved 2007/10/02.