4,5-Dihydrothiazol-2-amine monohydrobromide

Base Information

• Chemical Name: 4,5-Dihydrothiazol-2-amine monohydrobromide
• CAS No.: 13483-03-9
• Molecular Formula: C3H6 N2 S . Br H
• Molecular Weight: 183.072
• Hs Code.: 2934100090
• European Community (EC) Number: 236-790-0
• UNII: W6XL9MV32F
• DSSTox Substance ID: DTXSID80158997
• Mol file: 13483-03-9.mol

Synonyms:13483-03-9;4,5-Dihydrothiazol-2-amine monohydrobromide;2-Aminothiazoline hydrobromide;2-iminothiazolidine hydrobromide;2-AT;EINECS 236-790-0;2-Thiazolamine, 4,5-dihydro-, monohydrobromide;2-Thiazolamine,4,5-dihydro-, hydrobromide (1:1);W6XL9MV32F;4,5-Dihydro-2-thiazolamine hydrobromide;4,5-Dihydro-2-thiazolamine monohydrobromide;4,5-dihydro-1,3-thiazol-2-amine;hydrobromide;2-Thiazoline, 2-amino-, monohydrobromide;2-Thiazolamine, 4,5-dihydro-, monohydrobromide (9CI);C3H6N2S.BrH;UNII-W6XL9MV32F;4,5-dihydro-1,3-thiazol-2-amine,hydrobromide;SCHEMBL11599058;DTXSID80158997;2-Thiazoline, 2-amino-, hydrobromide;AKOS003726183;AKOS026677427;LS-151850;2-Thiazoline, 2-amino-, hydrobromide (6CI,7CI);F8889-9373;2-THIAZOLAMINE, 4,5-DIHYDRO-, HYDROBROMIDE (1:1)

Chemical Property of 4,5-Dihydrothiazol-2-amine monohydrobromide

Chemical Property:

• Vapor Pressure: 0.105mmHg at 25°C
• Boiling Point: 221.8°Cat760mmHg
• Flash Point: 87.9°C
• PSA: 61.18000
• Density: 1.5g/cm³
• LogP: 1.64420
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 181.95133
• Heavy Atom Count: 7
• Complexity: 78.9

Purity/Quality:

98%Min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CSC(=N1)N.Br

Technology Process of 4,5-Dihydrothiazol-2-amine monohydrobromide

There total 3 articles about 4,5-Dihydrothiazol-2-amine monohydrobromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

potassium thioacyanate (333-20-0) + 2-bromoethylamine hydrobromide (2576-47-8) → bromhydrate de 2-amino Δ1-thiazoline (13483-03-9)

Guidance literature:

In water; for 50h; Heating;

DOI:10.1007/BF00479384

Reference yield:

S-2-bromoethylisothiourea hydrobromide (80410-54-4) + thiourea (17356-08-0) → bromhydrate de 2-amino Δ1-thiazoline (13483-03-9) + ethylenebisisothiuronium dihydrobromide (6943-65-3)

Guidance literature:

In ethanol; at 100 ℃; Rate constant; sealed capillaries, other temperature (70, 80, 90 deg C), lgA, activation energy;

Reference yield:

→ bromhydrate de 2-amino Δ1-thiazoline (13483-03-9)

Guidance literature:

S-Aminoaethyl-isothiuroniumbromid-hydrobromid (AET);

upstream raw materials:

potassium thioacyanate

2-bromoethylamine hydrobromide

S-2-bromoethylisothiourea hydrobromide

thiourea

Downstream raw materials:

2-Bromo-2-(4-chloro-phenyl)-N-(4,5-dihydro-thiazol-2-yl)-acetamide

2-imino-N-phenylthiazolidinecarbothioamide

2-Bromo-N-(4,5-dihydro-thiazol-2-yl)-2-p-tolyl-acetamide

2-Bromo-N-(4,5-dihydro-thiazol-2-yl)-2-phenyl-acetamide

Refernces

• 1、 Tkachenko, S. E.,Sal'nikov, D. I.,Lys, Ya. I.,Fedoseev, V. M.,Zhurilin, V. S.. "S-DERIVATIVES OF THIOUREA. XX. REACTION OF THIOUREA WITH TERMINAL DIBROMOALKANES". . p. 878 - 884. Retrieved 2007/10/02.
• 2、 Bitny-Szlachto. "Quantitative paper chromatography of 1-aminothia- zolin and its application in studies of transformations of S-aminoethylisthiuronium bromide hydrobromide (AET)". . p. 411 - 418. Retrieved 2007/10/05.