Z-TYR-TYR-OH

Base Information

• Chemical Name: Z-TYR-TYR-OH
• CAS No.: 10417-83-1
• Molecular Formula: C26H26 N2 O7
• Molecular Weight: 478.502
• Mol file: 10417-83-1.mol

Synonyms:Tyrosine,N-(N-carboxy-L-tyrosyl)-, N-benzyl ester (6CI,7CI); Tyrosine,N-(N-carboxy-L-tyrosyl)-, N-benzyl ester, L- (8CI)

Chemical Property of Z-TYR-TYR-OH

Chemical Property:

• Melting Point: 148 °C
• Boiling Point: 830.5±65.0 °C(Predicted)
• PKA: 3.09±0.10(Predicted)
• PSA: 145.19000
• Density: 1.354±0.06 g/cm3(Predicted)
• LogP: 3.52920
• Storage Temp.: -15°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

Z-Tyr-Tyr-OH ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Z-Tyr-Tyr-OH is an oxytocin inhibitor.

Technology Process of Z-TYR-TYR-OH

There total 6 articles about Z-TYR-TYR-OH which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-(O-acetyl-N-benzyloxycarbonyl-L-tyrosyl)-L-tyrosine ethyl ester (6425-74-7) → N-(N-benzyloxycarbonyl-L-tyrosyl)-L-tyrosine (10417-83-1)

Guidance literature:

With sodium hydroxide;

Reference yield:

L-tyrosine ethyl ester (949-67-7) → N-(N-benzyloxycarbonyl-L-tyrosyl)-L-tyrosine (10417-83-1)

Guidance literature:

Multi-step reaction with 2 steps

1: ethyl acetate

2: aq. NaOH solution

With sodium hydroxide; ethyl acetate;

Reference yield:

O-acetyl-N-benzyloxycarbonyl-L-tyrosyl chloride (51514-08-0) → N-(N-benzyloxycarbonyl-L-tyrosyl)-L-tyrosine (10417-83-1)

Guidance literature:

Multi-step reaction with 2 steps

1: ethyl acetate

2: aq. NaOH solution

With sodium hydroxide; ethyl acetate;

upstream raw materials:

N-(O-acetyl-N-benzyloxycarbonyl-L-tyrosyl)-L-tyrosine ethyl ester

N-(N-benzyloxycarbonyl-L-tyrosyl)-L-tyrosine ethyl ester

L-tyrosine ethyl ester

O-acetyl-N-benzyloxycarbonyl-L-tyrosyl chloride

Downstream raw materials:

Z-L-Tyr-L-Tyr-OMe

N-(N-benzyloxycarbonyl-L-tyrosyl)-L-tyrosine ethyl ester

N-L-tyrosyl-L-tyrosine methyl ester; hydrochloride

N-L-tyrosyl-L-tyrosine ethyl ester; hydrochloride