Methyl 2-methoxytetrafluoropropionate

Base Information

• Chemical Name: Methyl 2-methoxytetrafluoropropionate
• CAS No.: 10186-63-7
• Molecular Formula: C5H6 F4 O3
• Molecular Weight: 190.094
• Hs Code.: 2918990090
• DSSTox Substance ID: DTXSID20379548
• Nikkaji Number: J1.638.480A
• Mol file: 10186-63-7.mol

Synonyms:Methyl 2-methoxytetrafluoropropionate;10186-63-7;methyl 2,3,3,3-tetrafluoro-2-methoxypropanoate;Methyl tetrafluoro-2-(methoxy)propionate;methyl 2-methoxytetrafluoropropanoate;Propanoic acid, 2,3,3,3-tetrafluoro-2-methoxy-, methyl ester;CH3OCF(CF3)COOMe;CF3CF(OCH3)COOCH3;SCHEMBL5960637;DTXSID20379548;MFCD00155951;AKOS001270594;AKOS017343590;FT-0676774;Z104484390;2,3,3,3-Tetrafluoro-2-methoxypropanoic acid methyl ester

Chemical Property of Methyl 2-methoxytetrafluoropropionate

Chemical Property:

• Vapor Pressure: 2.24mmHg at 25°C
• Refractive Index: 1.332
• Boiling Point: 161.7°Cat760mmHg
• Flash Point: 50.8°C
• PSA: 35.53000
• Density: 1.331g/cm³
• LogP: 1.03390
• XLogP3: 1.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 3
• Exact Mass: 190.02530670
• Heavy Atom Count: 12
• Complexity: 178

Purity/Quality:

98%,99%, ^*data from raw suppliers

Methyl2-Methoxytetrafluoropropionate ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC(=O)C(C(F)(F)F)(OC)F

Technology Process of Methyl 2-methoxytetrafluoropropionate

There total 14 articles about Methyl 2-methoxytetrafluoropropionate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

methanol (67-56-1) + Hexafluoropropene oxide (428-59-1,25038-02-2) → 2-fluoro-2-methoxy trifluoropropanoic acid methyl ester (10186-63-7)

Guidance literature:

With sodium carbonate; at 20 ℃;

Reference yield: 94.0%

methanol (67-56-1) + α-methoxytetrafluoropropionyl fluoride (85036-47-1) → 2-fluoro-2-methoxy trifluoropropanoic acid methyl ester (10186-63-7)

Guidance literature:

at 10 ℃;

DOI:10.1007/BF00961240

Reference yield: 87.0%

Hexafluoropropene oxide (428-59-1,25038-02-2) → 2-fluoro-2-methoxy trifluoropropanoic acid methyl ester (10186-63-7)

Guidance literature:

In methanol; water;

upstream raw materials:

methanol

Hexafluoropropene oxide

α-methoxytetrafluoropropionyl fluoride

2,3-epoxyperfluoropentane

Downstream raw materials:

Methyl fluoride

methyl 3,3,3-trifluoropyruvate

N,N-dimethyl-aniline

N-methylaniline

Refernces

• 1、 Lipovská, Pavlína,Rathouská, Lucie,?im?nek, Ond?ej,Ho?ek, Jan,Kola?íková, Viola,Rybá?ková, Markéta,Cva?ka, Josef,Svoboda, Martin,Kví?ala, Jaroslav. "Synthesis and catalytic activity of ruthenium complexes modified with chiral racemic per- and polyfluorooxaalkanoates". . p. 14 - 22. Retrieved 2016.
• 2、 -. "FIVE-MEMBERED CYCLIC ANION USE THEREOF AS AN ELECTROLYTE". Paragraph 0085. . Retrieved 2015/11/28.