Chloromethylphosphonothioic dichloride

Base Information

• Chemical Name: Chloromethylphosphonothioic dichloride
• CAS No.: 1983-27-3
• Molecular Formula: CH2 Cl3 P S
• Molecular Weight: 183.426
• Hs Code.: 2930909090
• DSSTox Substance ID: DTXSID00342710
• Wikidata: Q82113643
• Mol file: 1983-27-3.mol

Synonyms:Chloromethylphosphonothioic dichloride;1983-27-3;dichloro-(chloromethyl)-sulfanylidene-lambda5-phosphane;SCHEMBL11418474;DTXSID00342710;(chloromethyl)thiophosphoryl chloride;MFCD00015876;(Chloromethyl)phosphonothioic dichloride;CHLOROMETHYLPHOSPHONOTHIOICDICHLORIDE;FT-0693148

Chemical Property of Chloromethylphosphonothioic dichloride

Chemical Property:

• Vapor Pressure: 0.275mmHg at 25°C
• Refractive Index: 1.548
• Boiling Point: 210.7°Cat760mmHg
• Flash Point: 81.2°C
• PSA: 41.90000
• Density: 1.649g/cm³
• LogP: 3.62040
• Sensitive.: Moisture Sensitive
• XLogP3: 3.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 181.868041
• Heavy Atom Count: 6
• Complexity: 74.9

Purity/Quality:

98%,99%, ^*data from raw suppliers

CHLOROMETHYLPHOSPHONOTHIOIC DICHLORIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): R14-20/21/22-34:
• Hazard Codes: R14-20/21/22-34:
• Statements: 14-20/21/22-34
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(P(=S)(Cl)Cl)Cl

Technology Process of Chloromethylphosphonothioic dichloride

There total 4 articles about Chloromethylphosphonothioic dichloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

chloromethylphosphonic dichloride (1983-26-2) → (chloromethyl)phosphonothioic acid dichloride (1983-27-3)

Guidance literature:

With tetraphosphorus decasulfide; at 175 ℃;

DOI:10.1002/hc.21474

Reference yield: 13.9%

[1,3,5]trithiane (291-21-4) → (chloromethyl)phosphonothioic acid dichloride (1983-27-3)

Guidance literature:

With phosphorus trichloride; In neat (no solvent); at 245 ℃; for 3h;

Reference yield:

chloromethylphosphonic dichloride (1983-26-2) → (chloromethyl)phosphonothioic acid dichloride (1983-27-3)

Guidance literature:

at 180 ℃;

DOI:10.1097/01.LAB.0000017165.26718.60

upstream raw materials:

[1,3,5]trithiane

chloromethylphosphonic dichloride

Downstream raw materials:

N-(phosphonemethyl)glycine

C₁₁H₁₆ClN₂O₃PS

C₁₀H₁₄ClN₂O₃PS

C₁₀H₁₃Cl₂N₂O₃PS

Refernces

• 1、 Groenweghe,Payne. "". . p. 1811. Retrieved 1961.
• 2、 Antczak, Monika I.,Montchamp, Jean-Luc. "Mild synthesis of organophosphorus compounds: Reaction of phosphorus-containing carbenoids with organoboranes". supporting information; experimental part. p. 977 - 980. Retrieved 2009/04/10.
• 3、 Golovanov, A. V.,Maselnnikov, I. G.,Kornilova, T. V.,Kirichenko, L. N.,Lavrent'ev, A. N.. "REACTION OF PHOSPHORUS TRICHLORIDE WITH s-TRITHIANE (TRITHIOFORMALDEHYDE)". . p. 847. Retrieved 2007/10/02.