D-2,3-Diaminopropionic acid

Base Information

• Chemical Name: D-2,3-Diaminopropionic acid
• CAS No.: 1915-96-4
• Molecular Formula: C₃H₈N₂O₂
• Molecular Weight: 104.109
• Mol file: 1915-96-4.mol

Synonyms:D-2,3-Diaminopropionic acid;D-2-Amino-b-alanine;

Chemical Property of D-2,3-Diaminopropionic acid

Chemical Property:

• Vapor Pressure: 4.58E-05mmHg at 25°C
• Refractive Index: 1.522
• Boiling Point: 325.6 °C at 760 mmHg
• Flash Point: 150.7 °C
• PSA: 89.34000
• Density: 1.294 g/cm³
• LogP: -0.24240
• Storage Temp.: 2-8°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

(R)-2,3-Diaminopropanoicacid 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of D-2,3-Diaminopropionic acid

There total 38 articles about D-2,3-Diaminopropionic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

haloirciniamide A → (S)-2,3-diaminopropionic acid (515-94-6,1915-96-4,4033-39-0,6018-54-8) + L-isoserine (565-71-9,632-11-1,632-12-2,632-13-3) + (2R)-aspartic acid (1783-96-6,25608-40-6,27881-03-4,32505-46-7,52526-39-3)

Guidance literature:

haloirciniamide A; With hydrogenchloride; In water; at 110 ℃; for 15h;

With sodium hydrogencarbonate; N-(2,4-dinitro-5-fluorophenyl)-L-alaninamide; In water; acetone; at 40 ℃; for 1h;

DOI:10.3390/MD18080396

Reference yield:

(11S)-cyclocinamide A (194427-76-4) → (S)-2,3-diaminopropionic acid (515-94-6,1915-96-4,4033-39-0,6018-54-8) + L-isoserine (565-71-9,632-11-1,632-12-2,632-13-3) + L-Aspartic acid (56-84-8,25608-40-6,27881-03-4,32505-46-7,52526-39-3) + 5-bromo-DL-tryptophan (6548-09-0,25197-99-3,93299-40-2)

Guidance literature:

With hydrogenchloride; water; In phenol; at 110 ℃; for 4h; Inert atmosphere;

DOI:10.1021/ol300576n

Reference yield:

coprisamide C → D-Alanine (338-69-2,25191-17-7,18875-37-1) + L-valine (72-18-4,25609-85-2,7004-03-7,921-10-8) + (S)-2,3-diaminopropionic acid (515-94-6,1915-96-4,4033-39-0,6018-54-8) + D-Serine (312-84-5,83245-15-2) + (R)-leucine (328-38-1,21675-61-6,25248-98-0,70-45-1) + (2S,3S)-3-methylaspartic acid (6061-13-8)

Guidance literature:

With hydrogenchloride; In water; at 100 ℃; for 2h;

DOI:10.1021/acs.jnatprod.0c00864

upstream raw materials:

(R)-2,3-bis-(2-chloro-acetylamino)-propionic acid

N^α-Tos-D-A₂pr

(2R)-aspartic acid

L-3-acetyl-amino-2-amino-propionic acid

Downstream raw materials:

L-2-Amino-3-ureido-propanoic acid

N^β-(benzyloxycarbonyl)-L-α,β-diaminopropionic acid

C₄H₁₀N₂O₂

methyl (S)-2,3-diaminopropanoate

Refernces

• 1、 Abegaz, Berhanu M.,Nunn, Peter B.,Bruyn, Andre De,Lambein, Fernand. "THERMAL ISOMERIZATION OF N-OXALYL DERIVATIVES OF DIAMINO ACIDS". . p. 1121 - 1124. Retrieved 1993.
• 2、 Rao. "". . p. 5218,5219. Retrieved 1975.
• 3、 Karrer. "-". . p. 957. Retrieved 1923.
• 4、 Fernández, Rogelio,Bayu, Asep,Hadi, Tri Aryono,Bueno, Santiago,Pérez, Marta,Cuevas, Carmen,Putra, Masteria Yunovilsa. "Unique polyhalogenated peptides from the marine sponge Ircinia sp.". . . Retrieved 2020/08/28.