3,5-diamino-4-chloro-2-(2-hydroxyphenyl)diazenylbenzoic acid

Base Information

• Chemical Name: 3,5-diamino-4-chloro-2-(2-hydroxyphenyl)diazenylbenzoic acid
• CAS No.: 1426244-74-7
• Molecular Formula: C₁₃H₁₁ClN₄O₃
• Molecular Weight: 306.708
• Mol file: 1426244-74-7.mol

Synonyms:3,5-diamino-4-chloro-2-(2-hydroxyphenyl)diazenylbenzoic acid

Chemical Property of 3,5-diamino-4-chloro-2-(2-hydroxyphenyl)diazenylbenzoic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,5-diamino-4-chloro-2-(2-hydroxyphenyl)diazenylbenzoic acid

There total 2 articles about 3,5-diamino-4-chloro-2-(2-hydroxyphenyl)diazenylbenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

2-amino-phenol (95-55-6) + 3,5-diamino-4-chlorobenzoic acid (69236-82-4) → 3,5-diamino-4-chloro-2-(2-hydroxyphenyl)diazenylbenzoic acid (1426244-74-7)

Guidance literature:

2-amino-phenol; With hydrogenchloride; sodium nitrite; In water; at 10 ℃; for 1.25h;

3,5-diamino-4-chlorobenzoic acid; With sodium acetate; In ethanol; water; for 3.5h; pH=6;

DOI:10.1007/s10593-013-1165-9

Reference yield:

3,5-diamino-4-chlorobenzoic acid isobutyl ester (32961-44-7) → 3,5-diamino-4-chloro-2-(2-hydroxyphenyl)diazenylbenzoic acid (1426244-74-7)

Guidance literature:

Multi-step reaction with 2 steps

1.1: sodium hydroxide; water / ethanol / 1 h

2.1: hydrogenchloride; sodium nitrite / water / 1.25 h / 10 °C

2.2: 3.5 h / pH 6

With hydrogenchloride; water; sodium hydroxide; sodium nitrite; In ethanol; water;

DOI:10.1007/s10593-013-1165-9

Reference yield: 51.0%

3,5-diamino-4-chloro-2-(2-hydroxyphenyl)diazenylbenzoic acid (1426244-74-7) → 6-amino-7-chloro-2-(2-hydroxyphenyl)-2H-benzotriazole-4-carboxylic acid (1426244-82-7)

Guidance literature:

With copper(ll) sulfate pentahydrate; ammonia; In water; isopropyl alcohol; for 10h; Reflux;

DOI:10.1007/s10593-013-1165-9

upstream raw materials:

2-amino-phenol

3,5-diamino-4-chlorobenzoic acid

3,5-diamino-4-chlorobenzoic acid isobutyl ester

Downstream raw materials:

6-amino-7-chloro-2-(2-hydroxyphenyl)-2H-benzotriazole-4-carboxylic acid

6-amino-2-(2-hydroxyphenyl)-2H-benzotriazole-4-carboxylic acid

6-acetylamino-7-chloro-2-(2-hydroxyphenyl)-2H-benzotriazole-4-carboxylic acid

2-(2-acetoxyphenyl)-6-acetylamino-7-chloro-2H-benzotriazole-4-carboxylic acid

Refernces