4-Fluoro-3-(trifluoromethyl)benzene-1-sulfonyl chloride

Base Information

• Chemical Name: 4-Fluoro-3-(trifluoromethyl)benzene-1-sulfonyl chloride
• CAS No.: 1682-10-6
• Molecular Formula: C₇H₃ClF₄O₂S
• Molecular Weight: 262.612
• Hs Code.: 2904909090
• European Community (EC) Number: 679-046-4
• DSSTox Substance ID: DTXSID00372133
• Wikidata: Q72477280
• Mol file: 1682-10-6.mol

Synonyms:1682-10-6;4-fluoro-3-(trifluoromethyl)benzenesulfonyl Chloride;4-fluoro-3-(trifluoromethyl)benzene-1-sulfonyl chloride;4-Fluoro-3-(trifluoromethyl)benzenesulphonyl chloride;Benzenesulfonyl chloride, 4-fluoro-3-(trifluoromethyl)-;4-Fluoro-3-(trifluoromethyl)-benzenesulfonyl chloride;5-(chlorosulphonyl)-2-fluorobenzotrifluoride;SCHEMBL67150;4-Fluoro-3-(trifluoromethyl)benzenesulfonylchloride;4-fluoro-3-trifluoromethyl-benzenesulfonyl chloride;DTXSID00372133;BBL102719;MFCD01091001;STL556525;AKOS005063805;AM62490;CS-W012474;PS-10858;F1127;FT-0678381;EN300-54679;A24246;4-Fluoro-3-trifluoromethylbenzenesulfonyl chloride;4-fluoro-3-(trifluormethyl)-benzenesulfonyl chloride;4-Fluoro-3-(trifluoromethyl)phenylsulfonyl chloride;J-515360;4-fluoro-3-(trifluoromethyl)benzene-1-sulfonylchloride;Benzenesulfonylchloride,4-fluoro-3-(trifluoromethyl)-;4-fluoro-3-(trifluoromethyl)benzene-1-sulphonyl chloride;4-FLUORO-3-(TRIFLUOROMETHYL)BENZENESULPHONYLCHLORIDE;4-fluoro-3-(trifluoromethyl)benzenesulphonyl chloride, AldrichCPR

Chemical Property of 4-Fluoro-3-(trifluoromethyl)benzene-1-sulfonyl chloride

Chemical Property:

• Vapor Pressure: 0.00791mmHg at 25°C
• Refractive Index: 1.467
• Boiling Point: 276.8°Cat760mmHg
• Flash Point: 121.2°C
• PSA: 42.52000
• Density: 1.603g/cm³
• LogP: 3.85280
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Sensitive.: Moisture Sensitive
• XLogP3: 3.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 1
• Exact Mass: 261.9478409
• Heavy Atom Count: 15
• Complexity: 321

Purity/Quality:

99% ^*data from raw suppliers

4-Fluoro-3-(trifluoromethyl)benzenesulfonyl Chloride ^*data from reagent suppliers

Safty Information:

• Hazard Codes: C,Xi
• Statements: 36
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=C(C=C1S(=O)(=O)Cl)C(F)(F)F)F
• Use Description: 4-Fluoro-3-(trifluoromethyl)benzenesulfonyl chloride, a chemical compound, has various applications in different fields. In the pharmaceutical industry, it is employed as a versatile reagent in the synthesis of pharmaceuticals, specifically in the production of sulfonyl chloride-containing drugs. These drugs can have applications in treating a wide range of medical conditions. In the field of agrochemicals, it may serve as an intermediate in the production of pesticides and herbicides, contributing to crop protection and pest control. Furthermore, in the chemical research and development sector, it plays a crucial role as a building block for the creation of novel compounds and materials with unique properties. Its versatility and reactivity make 4-Fluoro-3-(trifluoromethyl)benzenesulfonyl chloride a valuable tool in pharmaceutical, agricultural, and chemical research, facilitating the development of new products and advancements in various industries.

Technology Process of 4-Fluoro-3-(trifluoromethyl)benzene-1-sulfonyl chloride

There total 1 articles about 4-Fluoro-3-(trifluoromethyl)benzene-1-sulfonyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 4-fluoro-3-(trifluoromethyl)benzene-1-sulphonyl chloride (1682-10-6)

Guidance literature:

Reference yield:

4-fluoro-3-(trifluoromethyl)benzene-1-sulphonyl chloride (1682-10-6) + 3-(6-(5-amino-6-methoxypyridin-3-yl)-4-oxoquinazolin-3(4H)-yl)-N,2-dimethylpropanamide → C26H23F4N5O5S

Guidance literature:

With pyridine; at 25 ℃; for 10h;

Reference yield:

4-fluoro-3-(trifluoromethyl)benzene-1-sulphonyl chloride (1682-10-6) + 2,4-difluoro-3-iodoaniline (1437316-91-0) → N-(2,4-difluoro-3-iodophenyl)-4-fluoro-3-(trifluoromethyl)benzenesulfonamide

Guidance literature:

With pyridine; at 20 ℃;

Refernces

• 1、 -. "AMINOTETRAHYDROINDAZOLOACETIC ACIDS". Page/Page column 27. . Retrieved 2010/02/17.