[(2E,4E)-4-Methyl-2,4-hexadienyl]phosphonic Acid Diethyl Ester

Base Information Edit

Chemical Name:[(2E,4E)-4-Methyl-2,4-hexadienyl]phosphonic Acid Diethyl Ester
CAS No.:104701-95-3
Molecular Formula:C₁₁H₂₁O₃P
Molecular Weight:232.26
Hs Code.:
Mol file:104701-95-3.mol

Synonyms:(2E,4E)-4-Methylhexa-2,4-dienylphosphonic acid diethylester

Suppliers and Price of [(2E,4E)-4-Methyl-2,4-hexadienyl]phosphonic Acid Diethyl Ester

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
[(2E,4E)-4-Methyl-2,4-hexadienyl]phosphonicAcidDiethylEster
100mg
$ 1320.00

Medical Isotopes, Inc.
[(2E,4E)-4-Methyl-2,4-hexadienyl]phosphonicAcidDiethylEster
100 mg
$ 2200.00

Total 1 raw suppliers

Chemical Property of [(2E,4E)-4-Methyl-2,4-hexadienyl]phosphonic Acid Diethyl Ester Edit

Chemical Property:

Solubility.:Dichloromethane, Ethyl Acetate

Purity/Quality:

99% ^*data from raw suppliers

[(2E,4E)-4-Methyl-2,4-hexadienyl]phosphonicAcidDiethylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses [(2E,4E)-4-Methyl-2,4-hexadienyl]phosphonic Acid Diethyl Ester is a reactant used in the preparation of cytochalasin.

Technology Process of [(2E,4E)-4-Methyl-2,4-hexadienyl]phosphonic Acid Diethyl Ester

There total 4 articles about [(2E,4E)-4-Methyl-2,4-hexadienyl]phosphonic Acid Diethyl Ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: 276690-19-8
(2E,4E)-1-Bromo-4-methylhexa-2,4-diene

: 122-52-1
triethyl phosphite

: 104701-95-3
(2E,4E)-4-Methylhexa-2,4-dienylphosphonic acid diethylester

Guidance literature:: at 160 ℃;

Reference yield:

: 497-03-0
2-methylbut-2-enal

: 104701-95-3
(2E,4E)-4-Methylhexa-2,4-dienylphosphonic acid diethylester

Guidance literature:: Multi-step reaction with 4 steps

1.1: NaH / tetrahydrofuran / 2 h / 0 °C

1.2: 71 percent / tetrahydrofuran / -78 - 20 °C

2.1: 99 percent / DIBAL / toluene; diethyl ether / 1 h / -78 °C

3.1: 93 percent / PBr₃ / diethyl ether / 0 °C

4.1: 63 percent / 160 °C

With phosphorus tribromide; sodium hydride; diisobutylaluminium hydride; In tetrahydrofuran; diethyl ether; toluene; 1.1: Metallation / 1.2: Condensation / 2.1: Reduction / 3.1: Substitution / 4.1: Alkylation;

Reference yield:

: 149400-42-0,90107-62-3
ethyl (2E,4E)-4-methylhexa-2,4-dienoate

: 104701-95-3
(2E,4E)-4-Methylhexa-2,4-dienylphosphonic acid diethylester

Guidance literature:: Multi-step reaction with 3 steps

1: 99 percent / DIBAL / toluene; diethyl ether / 1 h / -78 °C

2: 93 percent / PBr₃ / diethyl ether / 0 °C

3: 63 percent / 160 °C

With phosphorus tribromide; diisobutylaluminium hydride; In diethyl ether; toluene; 1: Reduction / 2: Substitution / 3: Alkylation;