methyl 2-ethylphenylcarbamate

Base Information

• Chemical Name: methyl 2-ethylphenylcarbamate
• CAS No.: 27058-77-1
• Molecular Formula: C₁₀H₁₃NO₂
• Molecular Weight: 179.219
• Mol file: 27058-77-1.mol

Synonyms:methyl 2-ethylphenylcarbamate

Chemical Property of methyl 2-ethylphenylcarbamate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of methyl 2-ethylphenylcarbamate

There total 3 articles about methyl 2-ethylphenylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

2-[2-(2-methoxyethoxy)ethoxy]ethyl methyl carbonate (160852-85-7) + ortho-ethylaniline (578-54-1) → (2-ethyl-phenyl)-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethyl}-amine + N,N-dimethyl ortho-ethylaniline (6126-96-1) + N-methyl-2-ethylphenylamine (1821-38-1) + methyl 2-ethylphenylcarbamate (27058-77-1)

Guidance literature:

With ethyltriphenylphosphonium iodide; at 170 ℃; for 1.25h; Further byproducts given;

DOI:10.1021/jo060674d

Reference yield:

ortho-ethylaniline (578-54-1) + methyl chloroformate (79-22-1) → methyl 2-ethylphenylcarbamate (27058-77-1)

Guidance literature:

With potassium carbonate; In dichloromethane; Ambient temperature;

DOI:10.1248/cpb.46.1286

Reference yield:

→ methyl 2-ethylphenylcarbamate (27058-77-1)

Guidance literature:

aus 2-Aethyl-phenylisocyanat, Methanol;

upstream raw materials:

ortho-ethylaniline

methyl chloroformate

2-[2-(2-methoxyethoxy)ethoxy]ethyl methyl carbonate

Downstream raw materials:

Chloromethyl-(2-ethyl-phenyl)-carbamic acid methyl ester

methyl 4-(chlorosulfonyl)-2-ethylphenylcarbamate

methyl 2-ethyl-4-sulfamoylphenylcarbamate

(S)-methyl 2-ethyl-4-(2-oxo-4-phenylimidazolidin-1-ylsulfonyl)phenylcarbamate

Refernces

• 1、 Selva, Maurizio,Perosa, Alvise,Tundo, Pietro,Brunelli, Davide. "Selective N,N-dimethylation of primary aromatic amines with methyl alkyl carbonates in the presence of phosphonium salts". . p. 5770 - 5773. Retrieved 2007/10/03.