2-ethylpentanedinitrile

Base Information

• Chemical Name: 2-ethylpentanedinitrile
• CAS No.: 74261-49-7
• Molecular Formula: C₇H₁₀N₂
• Molecular Weight: 122.17
• Mol file: 74261-49-7.mol

Synonyms:4-cyanohexanenitrile

Chemical Property of 2-ethylpentanedinitrile

Chemical Property:

• Vapor Pressure: 0.00218mmHg at 25°C

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-ethylpentanedinitrile

There total 4 articles about 2-ethylpentanedinitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

2-Ethyl-2-nitro-pentanedinitrile (74261-42-0) → 4-cyanohexanenitrile (74261-49-7)

Guidance literature:

With 1-Benzyl-1,4-dihydronicotinamide; In benzene; for 24h; Ambient temperature; Irradiation;

DOI:10.1021/ja00528a062

Reference yield:

1,3-pentanediol (3174-67-2) → 4-cyanohexanenitrile (74261-49-7)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrogen bromide / 110 °C

2: aqueous ethanol

With ethanol; hydrogen bromide;

Reference yield:

4-ethyl-[1,3]dioxane (1121-61-5) → 4-cyanohexanenitrile (74261-49-7)

Guidance literature:

Multi-step reaction with 3 steps

1: aqueous methanol.-sulfuric acid

2: hydrogen bromide / 110 °C

3: aqueous ethanol

With ethanol; sulfuric acid; hydrogen bromide;

upstream raw materials:

1,3-dibromo-pentane

potassium cyanide

2-Ethyl-2-nitro-pentanedinitrile

4-ethyl-[1,3]dioxane

Refernces

• 1、 Ono, Noboru,Tamura, Rui,Kaji, Aritsune. "1-Benzyl-1,4-dihydronicotinamide as a Reagent for Replacing Aliphatic Nitro Groups by Hydrogen: An Electron-Transfer Chain Reaction". . p. 2851 - 2852. Retrieved 2007/10/02.