o-Methoxycinnamyl alcohol

Base Information

• Chemical Name: o-Methoxycinnamyl alcohol
• CAS No.: 1504-61-6
• Molecular Formula: C10H12 O2
• Molecular Weight: 164.204
• Hs Code.: 2909499000
• Mol file: 1504-61-6.mol

Synonyms:2-Propen-1-ol,3-(o-methoxyphenyl)- (7CI,8CI); 3-(2-Methoxyphenyl)-2-propen-1-ol;o-Methoxycinnamyl alcohol

Chemical Property of o-Methoxycinnamyl alcohol

Chemical Property:

• Vapor Pressure: 0.000363mmHg at 25°C
• Refractive Index: 1.577
• Boiling Point: 305.3°Cat760mmHg
• Flash Point: 139.4°C
• PSA: 29.46000
• Density: 1.08g/cm³
• LogP: 1.70070

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of o-Methoxycinnamyl alcohol

There total 27 articles about o-Methoxycinnamyl alcohol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

2-methoxycinnamaldehyde (1504-74-1) → 2-methoxycinnamyl alcohol (1504-61-6)

Guidance literature:

With Hf-based metal organic framework-808; In isopropyl alcohol; at 120 ℃; Inert atmosphere;

DOI:10.1016/j.mcat.2021.111405

Reference yield: 98.0%

(E)-3-(2-methoxyphenyl)propenal (60125-24-8) → (E)-3-(2-methoxyphenyl)prop-2-en-1-ol (1504-61-6,13523-28-9,114568-19-3)

Guidance literature:

With sodium formate; N-tosylethylenediamine; bis[dichloro(pentamethylcyclopentadienyl)iridium(III)]; at 80 ℃; for 0.4h;

DOI:10.1002/anie.200602122

Reference yield: 91.0%

2-allylanisole (3698-28-0) → (E)-3-(2-methoxyphenyl)prop-2-en-1-ol (1504-61-6,13523-28-9,114568-19-3)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; carbon dioxide; 2,5-di-tert-butyl-p-benzoquinone; water; In 1,4-dioxane; at 40 ℃; for 24h; under 30003 Torr; Inert atmosphere; Autoclave;

DOI:10.1002/chem.201403373

upstream raw materials:

2-methoxycinnamaldehyde

2-allylanisole

1-(2-methoxyphenyl)prop-2-en-1-ol

methyl 2-methoxycinnamate

Downstream raw materials:

(E)-3-(2-methoxyphenyl)propenal

(E)-1-(3-bromoprop-1-en-1-yl)-2-methoxybenzene

3-(2-methoxyphenyl)propan-1-ol

3-(2-methoxyphenyl)propanal

Refernces

• 1、 Wang, Rongzhou,Yue, Yuancheng,Qi, Jipeng,Liu, Shiyuan,Song, Ao,Zhuo, Shuping,Xing, Ling-Bao. "Ambient-pressure highly active hydrogenation of ketones and aldehydes catalyzed by a metal-ligand bifunctional iridium catalyst under base-free conditions in water". . p. 1 - 7. Retrieved 2021/05/17.
• 2、 Chen, Yi,Gao, Lu,Song, Xuanyi,Song, Zhenlei. "Intramolecular Sakurai Allylation of Geminal Bis(silyl) Enamide with Indolenine. A Diastereoselective Cyclization to Form Functionalized Hexahydropyrido[3,4- b]Indole". supporting information. p. 124 - 128. Retrieved 2021/01/13.