3-Phenyl-1-propylmagnesium bromide

Base Information

• Chemical Name: 3-Phenyl-1-propylmagnesium bromide
• CAS No.: 1462-75-5
• Molecular Formula: C9H11BrMg
• Molecular Weight: 223.395
• Hs Code.: 2931900090
• European Community (EC) Number: 627-041-2
• Mol file: 1462-75-5.mol

Synonyms:1462-75-5;3-Phenyl-1-propylmagnesium bromide;3-PHENYL PROPANE MAGNESIUM BROMIDE;magnesium;propylbenzene;bromide;3-phenylpropylmagnesium bromide;3-phenylpropyl-magnesium bromide;Magnesium, bromo(3-phenylpropyl)-;SCHEMBL1720;Phenylpropylmagnesium bromide;3-phenylpropyl magnesium bromide;(3-phenylpropyl)magnesium bromide;3-(phenyl)propylmagnesium bromide;3-phenyl-propyl magnesium bromide;JHUYNQGHNWXETM-UHFFFAOYSA-M;MFCD08064088;AKOS016017707;3-(Phenyl)propylmagnesium bromide, 0.50 M in 2-MeTHF;3-Phenyl-1-propylmagnesium bromide 0.5 M in Tetrahydrofuran

Chemical Property of 3-Phenyl-1-propylmagnesium bromide

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 0.00000
• Density: g/cm³
• LogP: 3.43240
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 221.98945
• Heavy Atom Count: 11
• Complexity: 70

Purity/Quality:

97% ^*data from raw suppliers

3-(Phenyl)propylmagnesiumbromide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: [CH2-]CCC1=CC=CC=C1.[Mg+2].[Br-]

Technology Process of 3-Phenyl-1-propylmagnesium bromide

There total 3 articles about 3-Phenyl-1-propylmagnesium bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

1-Bromo-3-phenylpropane (637-59-2) + magnesium (7439-95-4) → 3-phenylpropylmagnesium bromide (1462-75-5)

Guidance literature:

In tetrahydrofuran; for 1h; Inert atmosphere; Reflux;

DOI:10.1039/d2cc00446a

Reference yield:

1-Bromo-3-phenylpropane (637-59-2) → 3-phenylpropylmagnesium bromide (1462-75-5)

Guidance literature:

With magnesium; In diethyl ether; for 0.25h; Heating;

DOI:10.1039/DT9960002467

Reference yield:

→ 1-(4-hydroxyphenyl)-4-phenyl-1-butanol + 3-phenylpropylmagnesium bromide (1462-75-5)

Guidance literature:

upstream raw materials:

1-Bromo-3-phenylpropane

magnesium

Downstream raw materials:

1,1-Diphenylmethanol

1,1,4-triphenyl-1-butanol

1-(4-chloro-phenyl)-4-phenyl-1-[4]pyridyl-butan-1-ol

1-[1-(4-methoxy-phenyl)-4-phenyl-butyl]-piperidine

Refernces

• 1、 Zhou, Juan,Mock, Elliot D.,Al Ayed, Karol,Di, Xinyu,Kantae, Vasudev,Burggraaff, Lindsey,Stevens, Anna F.,Martella, Andrea,Mohr, Florian,Jiang, Ming,Van Der Wel, Tom,Wendel, Tiemen J.,Ofman, Tim P.,Tran, Yvonne,De Koster, Nicky,Van Westen, Gerard J.P.,Hankemeier, Thomas,Van Der Stelt, Mario. "Structure-Activity Relationship Studies of α-Ketoamides as Inhibitors of the Phospholipase A and Acyltransferase Enzyme Family". . p. 9340 - 9359. Retrieved 2020/10/19.
• 2、 Qin, Ling,Sharique, Mohammed,Tambar, Uttam K.. "Controllable, Sequential, and Stereoselective C-H Allylic Alkylation of Alkenes". supporting information. p. 17305 - 17313. Retrieved 2019/11/03.