Technology Process of C24H19NO2
There total 6 articles about C24H19NO2 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
C24H21NO2;
With
1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone; tert.-butyl lithium;
In
tetrahydrofuran; pentane;
at -78 ℃;
for 0.166667h;
Inert atmosphere;
With
ammonium chloride;
In
tetrahydrofuran; methanol; pentane;
at -78 - 20 ℃;
Inert atmosphere;
DOI:10.1016/j.tetlet.2013.05.098
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: potassium carbonate / water; isopropyl alcohol
2.1: thionyl chloride
3.1: methanesulfonyl chloride
4.1: sodium hydroxide / ethanol / 2 h / Heating
5.1: sodium hydride
6.1: tert.-butyl lithium; 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone / pentane; tetrahydrofuran / 0.17 h / -78 °C / Inert atmosphere
6.2: -78 - 20 °C / Inert atmosphere
With
1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone; thionyl chloride; tert.-butyl lithium; sodium hydride; potassium carbonate; methanesulfonyl chloride; sodium hydroxide;
In
tetrahydrofuran; ethanol; water; isopropyl alcohol; pentane;
DOI:10.1016/j.tetlet.2013.05.098
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: sodium hydroxide / ethanol / 2 h / Heating
2.1: sodium hydride
3.1: tert.-butyl lithium; 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone / pentane; tetrahydrofuran / 0.17 h / -78 °C / Inert atmosphere
3.2: -78 - 20 °C / Inert atmosphere
With
1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone; tert.-butyl lithium; sodium hydride; sodium hydroxide;
In
tetrahydrofuran; ethanol; pentane;
DOI:10.1016/j.tetlet.2013.05.098
