3-fluoro-N'-phenylbenzohydrazonoyl chloride

Base Information

• Chemical Name: 3-fluoro-N'-phenylbenzohydrazonoyl chloride
• CAS No.: 1416007-76-5
• Molecular Formula: C₁₃H₁₀ClFN₂
• Molecular Weight: 248.687
• Mol file: 1416007-76-5.mol

Synonyms:3-fluoro-N'-phenylbenzohydrazonoyl chloride

Chemical Property of 3-fluoro-N'-phenylbenzohydrazonoyl chloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-fluoro-N'-phenylbenzohydrazonoyl chloride

There total 4 articles about 3-fluoro-N'-phenylbenzohydrazonoyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C13H11FN2O → 3-fluoro-N'-phenylbenzohydrazonoyl chloride (1416007-76-5)

Guidance literature:

With tetrachloromethane; triphenylphosphine; In acetonitrile; at 20 ℃; Inert atmosphere;

DOI:10.1021/acs.orglett.7b01961

Reference yield:

1-(3-fluorobenzylidene)-2-phenylhydrazine (351-24-6) → 3-fluoro-N'-phenylbenzohydrazonoyl chloride (1416007-76-5)

Guidance literature:

With N-chloro-succinimide; dimethylsulfide; In dichloromethane; at -78 - 20 ℃; for 4h;

DOI:10.1021/ol303097j

Reference yield:

phenylhydrazine (100-63-0) → 3-fluoro-N'-phenylbenzohydrazonoyl chloride (1416007-76-5)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine / Inert atmosphere

2: triphenylphosphine; tetrachloromethane / acetonitrile / 20 °C / Inert atmosphere

With pyridine; tetrachloromethane; triphenylphosphine; In acetonitrile;

DOI:10.1021/acs.orglett.7b01961

upstream raw materials:

1-(3-fluorobenzylidene)-2-phenylhydrazine

phenylhydrazine

3-fluorobenzoyl chloride

Downstream raw materials:

tert-butyl 4'-tert-butyl-5'-(3-fluorophenyl)-2-oxo-2'-phenyl-2',4'-dihydrospiro[indoline-3,3'-pyrazole]-1-carboxylate

Refernces

• 1、 Liu, Honglei,Jia, Hao,Wang, Bo,Xiao, Yumei,Guo, Hongchao. "Synthesis of Spirobidihydropyrazole through Double 1,3-Dipolar Cycloaddition of Nitrilimines with Allenoates". . p. 4714 - 4717. Retrieved 2017/09/23.