2-Butanone, 4-(dimethylamino)- (6CI,7CI,8CI,9CI)

Base Information

• Chemical Name: 2-Butanone, 4-(dimethylamino)- (6CI,7CI,8CI,9CI)
• CAS No.: 2543-57-9
• Molecular Formula: C6H13 N O
• Molecular Weight: 115.175
• Hs Code.: 2922399090
• Mol file: 2543-57-9.mol

Synonyms:1-Dimethylamino-3-butanone;4-(Dimethylamino)-2-butanone

Chemical Property of 2-Butanone, 4-(dimethylamino)- (6CI,7CI,8CI,9CI)

Chemical Property:

• Boiling Point: 50-52 °C(Press: 13 Torr)
• PKA: 8.88±0.28(Predicted)
• PSA: 20.31000
• Density: 0.8636 g/cm3(Temp: 25 °C)
• LogP: 0.52710
• Storage Temp.: Inert atmosphere,Room Temperature

Purity/Quality:

98%Min ^*data from raw suppliers

4-(dimethylamino)-2-Butanone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 4-(dimethylamino)-2-Butanone is a useful building block extracted from volatile oil in Semen persicae-Flos carthami. 4-(dimethylamino)-2-Butanone is used as a component of lubricating oil used to improve the viscosity index and sludge dispersion properties of hydrogenated lithiated copolymers.

Technology Process of 2-Butanone, 4-(dimethylamino)- (6CI,7CI,8CI,9CI)

There total 18 articles about 2-Butanone, 4-(dimethylamino)- (6CI,7CI,8CI,9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

methyl vinyl ketone (78-94-4,25038-87-3) + dimethyl amine (124-40-3) → 1-Dimethylamino-3-butanon (2543-57-9)

Guidance literature:

With C₉H₁₄N₂O₃S; In water; at 20 ℃; for 0.416667h;

DOI:10.1002/jhet.5570450650

Reference yield: 83.1%

1,3-dimethylimidazolidine (14103-77-6) + dimethyl amine (124-40-3) + acetone (67-64-1) → 1-Dimethylamino-3-butanon (2543-57-9)

Guidance literature:

With acetic acid; In acetonitrile; for 10h; Reflux;

DOI:10.1002/cjoc.201100628

Reference yield:

4-dimethylamino-2-hydroxy-2-methyl-butyronitrile → hydrogen cyanide (74-90-8) + 1-Dimethylamino-3-butanon (2543-57-9)

Guidance literature:

Vakuumdestillation;

upstream raw materials:

formaldehyd

1-methoxybutan-3-one

N,N-dimethylammonium chloride

2-acetoacetic acid

Downstream raw materials:

1-acetoxybutan-3-one

4-carbethoxy-3-methyl-2-cyclohexen-1-one

5-dimethylamino-1t-phenyl-penten-⁽¹⁾-one-⁽³⁾

5-nitro-2-pentanone

Refernces

• 1、 Agbenyeke, Raphael Edem,Chung, Taek-Mo,Han, Seong Ho,Kim, Chang Gyoun,Lee, Ga Yeon,Lee, Young Kuk,Park, Bo Keun,Son, Seung Uk. "Synthesis and characterization of novel zinc precursors for ZnO thin film deposition by atomic layer deposition". . p. 4306 - 4314. Retrieved 2020.
• 2、 Guo, Yuan,An, Jing,Lu, Zhenhuan,Peng, Mengjiao. "A novel method for biomimetic synthesis of Mannich bases". experimental part. p. 1561 - 1564. Retrieved 2012/10/07.