2-n-Octyloxybenzoic acid

Base Information

• Chemical Name: 2-n-Octyloxybenzoic acid
• CAS No.: 27830-12-2
• Molecular Formula: C15H22O3
• Molecular Weight: 250.338
• Hs Code.: 2918990090
• Mol file: 27830-12-2.mol

Synonyms:Benzoicacid, o-(octyloxy)- (8CI);

Chemical Property of 2-n-Octyloxybenzoic acid

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.51
• Boiling Point: 376.923 °C at 760 mmHg
• Flash Point: 133.565 °C
• PSA: 46.53000
• Density: 1.037 g/cm³
• LogP: 4.12410

Purity/Quality:

99.9% ^*data from raw suppliers

2-(Octyloxy)benzoicacid 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-n-Octyloxybenzoic acid

There total 4 articles about 2-n-Octyloxybenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

2-octyloxybenzoic acid methyl ester (255062-85-2) → 2-octyloxybenzoic acid (27830-12-2)

Guidance literature:

With sodium hydroxide; In tetrahydrofuran; methanol; water; at 20 - 85 ℃;

Reference yield:

1-bromo-octane (111-83-1) → 2-octyloxybenzoic acid (27830-12-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 71 percent / K₂CO₃ / dimethylformamide / 24 h / 90 °C

2: 90 percent / NaOH / methanol / 2 h / Heating

With sodium hydroxide; potassium carbonate; In methanol; N,N-dimethyl-formamide;

DOI:10.1016/j.tet.2007.04.043

Reference yield:

methyl salicylate (119-36-8,8024-54-2) → 2-octyloxybenzoic acid (27830-12-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 71 percent / K₂CO₃ / dimethylformamide / 24 h / 90 °C

2: 90 percent / NaOH / methanol / 2 h / Heating

With sodium hydroxide; potassium carbonate; In methanol; N,N-dimethyl-formamide;

DOI:10.1016/j.tet.2007.04.043

upstream raw materials:

2-octyloxybenzoic acid methyl ester

1-bromo-octane

methyl salicylate

Downstream raw materials:

2-(octyloxy)-5-nitro-benzoic acid

methyl 4-(octyloxy)benzoate

N-hexyl-2-(octyloxy)-5-nitrobenzamide

N-hexyl-5-amino-2-(octyloxy)benzamide

Refernces

• 1、 -. "Preparation method of octylonium bromide". Paragraph 0022; 0024; 0027; 0029. . Retrieved 2019/07/04.
• 2、 Bialecki, Jason B.,Yuan, Li-Hua,Gong, Bing. "A branched, hydrogen-bonded heterodimer: a novel system for achieving high stability and specificity". . p. 5460 - 5469. Retrieved 2008/01/07.