DIHYDROPYRIDINE

Base Information

• Chemical Name: DIHYDROPYRIDINE
• CAS No.: 27790-75-6
• Molecular Formula: 2C₅H₅N*Cl₂Hg
• Molecular Weight: 429.699
• Mol file: 27790-75-6.mol

Synonyms:Dihydropyridines;

Chemical Property of DIHYDROPYRIDINE

Chemical Property:

• Vapor Pressure: 3.55mmHg at 25°C
• Refractive Index: 1.486
• Boiling Point: 152.1°Cat760mmHg
• Flash Point: 46.3°C
• PSA: 12.89000
• Density: 0.91g/cm³
• LogP: 2.68310

Purity/Quality:

99% ^*data from raw suppliers

1,4-DIHYDROPYRIDINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of DIHYDROPYRIDINE

There total 13 articles about DIHYDROPYRIDINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

bis(mesitylene)vanadium(0) (1272-71-5) → Tetrakis(pyridin)-dichlorovanadin(II) (25377-37-1,27790-75-6,82009-22-1) + 1,3,5-trimethyl-benzene (108-67-8)

Guidance literature:

With pyridine; 3-chloroprop-1-ene; In toluene; soln. of V-complex in toluene was treated with CH2=CHCH2Cl (inert atmosphere), the mixt. was stirred at room temp. for 24 h; the mother liquor contained org. compounds, products of the reaction of CH2=CHCH2Cl with either toluene or mesitylene (CLG-MS); filtered, ppt. was dissolved in pyridine, soln. was filtered and concd.to give the crystals of VCl2*4Py; identified by comparison of the IR spectrum with that of authentic sample;

DOI:10.1016/0022-328X(83)80106-5

Reference yield: 47.0%

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) + 1-bromo-hexane (111-25-1) → (E)-1-phenyl-1-octene (28665-60-3) + 2C5H5N*Br2Zn (25377-37-1,27790-75-6,82009-22-1)

Guidance literature:

With pyridine; zinc; bis(triphenylphosphine)nickel(II) chloride; In acetonitrile; at 65 ℃; for 4h;

Reference yield: 45.0%

Vanadium (III) chloride-(tris-tetrahydrofuran) (131063-11-1,16997-51-6,19559-06-9) + (trimethylsilyl)methylmagnesium chloride (13170-43-9) → Tetrakis(pyridin)-dichlorovanadin(II) (25377-37-1,27790-75-6,82009-22-1) + tetrakis(trimethylsilylmethyl)vanadium (41572-08-1) + magnesium chloride (7786-30-3)

Guidance literature:

In diethyl ether; 1 mol of complex was slowly added to an ether soln. of 2 mol RMgCl at -15°C, after 1 h the temp. was raised to room temp. (Ar atm.);; dioxane was added, ppt. was extd. with pentane; elem. anal.;;

DOI:10.1016/S0022-328X(00)82672-8

upstream raw materials:

pyridine

vanadium trichloride tristetrahydrofuran

pentafluorophenylmagnesium chloride

bis(mesitylene)vanadium⁽⁰⁾

Downstream raw materials:

pyridine

HgCl₂*pyridine

clinoatacamite

Refernces

• 1、 Lebedev, S. A.,Lopatina, V. S.,Luk'yanova, T. V.,Berestova, S. S.,Shifrina, R. R.,et al.. "REACTION OF ALKYL BROMIDES WITH STYRENE IN THE PRESENCE OF A NICKEL CATALYST". . p. 652 - 656. Retrieved 2007/10/02.
• 2、 Razuvaev, G.A.,Latyaeva, V.N.,Vyshinskaya, L.I.,Drobotenko, V.V.. "SYNTHESIS AND PROPERTIES OF COVALENT TRI- AND TETRAVALENT VANADIUM". . p. 169 - 182. Retrieved 2007/10/02.