Multi-step reaction with 3 steps
1.1: 2,2,6,6-tetramethylpiperidinylmagnesium chloride lithium chloride complex / tetrahydrofuran / 3 h / 20 °C / Inert atmosphere
1.2: 20 h / 60 °C / Inert atmosphere
2.1: 2,2,6,6-tetramethyl-piperidine; ethylmagnesium chloride / tetrahydrofuran / 24 h / 66 °C / Inert atmosphere
2.2: 26 h / 60 °C / Inert atmosphere
3.1: 2,2,6,6-tetramethylpiperidinylmagnesium chloride lithium chloride complex / tetrahydrofuran / 3 h / 20 °C / Inert atmosphere
3.2: 13 h / 60 °C / Inert atmosphere
With
2,2,6,6-tetramethyl-piperidine; 2,2,6,6-tetramethylpiperidinylmagnesium chloride lithium chloride complex; ethylmagnesium chloride;
In
tetrahydrofuran;
DOI:10.1021/ja205953g